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Microneedle-Based Delivery: An Overview of Current Applications and Trends
by
Donnelly, Ryan F.
, Guillot, Antonio José
, Montesinos, M. Carmen
, Garrigues, Teresa M.
, Cordeiro, Ana Sara
, Melero, Ana
in
Drug delivery systems
/ Drug dosages
/ Hydrogels
/ microneedle array
/ microneedles
/ Permeability
/ Pharmaceuticals
/ Review
/ Skin
/ stratum corneum
/ transdermal delivery
/ Transdermal medication
/ Trends
2020
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Microneedle-Based Delivery: An Overview of Current Applications and Trends
by
Donnelly, Ryan F.
, Guillot, Antonio José
, Montesinos, M. Carmen
, Garrigues, Teresa M.
, Cordeiro, Ana Sara
, Melero, Ana
in
Drug delivery systems
/ Drug dosages
/ Hydrogels
/ microneedle array
/ microneedles
/ Permeability
/ Pharmaceuticals
/ Review
/ Skin
/ stratum corneum
/ transdermal delivery
/ Transdermal medication
/ Trends
2020
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Do you wish to request the book?
Microneedle-Based Delivery: An Overview of Current Applications and Trends
by
Donnelly, Ryan F.
, Guillot, Antonio José
, Montesinos, M. Carmen
, Garrigues, Teresa M.
, Cordeiro, Ana Sara
, Melero, Ana
in
Drug delivery systems
/ Drug dosages
/ Hydrogels
/ microneedle array
/ microneedles
/ Permeability
/ Pharmaceuticals
/ Review
/ Skin
/ stratum corneum
/ transdermal delivery
/ Transdermal medication
/ Trends
2020
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Microneedle-Based Delivery: An Overview of Current Applications and Trends
Journal Article
Microneedle-Based Delivery: An Overview of Current Applications and Trends
2020
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Overview
Microneedle arrays (MNA) are considered as one of the most promising resources to achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally invasive, painless system which can bypass the stratum corneum, overcoming the potential drawbacks of subcutaneous injections and other transdermal delivery systems such as chemical enhancers, nano and microparticles, or physical treatments. As a trendy field in pharmaceutical and biomedical research, its applications are constantly evolving, even though they are based on very well-established techniques. The number of molecules administered by MNA are also increasing, with insulin and vaccines administration being the most investigated. Furthermore, MNA are being used to deliver cells and applied in other organs and tissues like the eyes and buccal mucosae. This review intends to offer a general overview of the current state of MNA research, focusing on the strategies, applications, and types of molecules delivered recently by these systems. In addition, some information about the materials and manufacturing processes is presented and safety data is discussed.
Publisher
MDPI AG,MDPI
Subject
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