Asset Details
Do you wish to reserve the book?
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Do you wish to request the book?
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Volatile versus propofol sedation after cardiac valve surgery: a single-center prospective randomized controlled trial
2024
Overview
Background
Optimal intensive care of patients undergoing valve surgery is a complex balancing act between sedation for monitoring and timely postoperative awakening. It remains unclear, if these requirements can be fulfilled by volatile sedations in intensive care medicine in an efficient manner. Therefore, this study aimed to assess the time to extubation and secondary the workload required.
Methods
We conducted a prospective randomized single-center trial at a tertiary university hospital to evaluate the postoperative management of open valve surgery patients. The study was randomized with regard to the use of volatile sedation compared to propofol sedation. Sedation was discontinued 60 min after admission for critical postoperative monitoring.
Results
We observed a significantly earlier extubation (91 ± 39 min vs. 167 ± 77 min;
p
< 0.001), eye-opening (86 ± 28 min vs. 151 ± 71 min;
p
< 0.001) and command compliance (93 ± 38 min vs. 164 ± 75 min;
p
< 0.001) using volatile sedation, which in turn was associated with a significantly increased workload of a median of 9:56 min (± 4:16 min) set-up time. We did not observe any differences in complications. Cardiopulmonary bypass time did not differ between the groups 101 (IQR 81; 113) versus 112 (IQR 79; 136) minutes
p
= 0.36.
Conclusions
Using volatile sedation is associated with few minutes additional workload in assembling and enables a significantly accelerated evaluation of vulnerable patient groups. Volatile sedation has considerable advantages and emerges as a safe sedation technique in our vulnerable study population.
Trial registration
: Clinical trials registration (NCT04958668) was completed on 1 July 2021.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V
