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Hepcidin: A Putative Iron-Regulatory Hormone Relevant to Hereditary Hemochromatosis and the Anemia of Chronic Disease
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Hepcidin: A Putative Iron-Regulatory Hormone Relevant to Hereditary Hemochromatosis and the Anemia of Chronic Disease
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Journal Article
Hepcidin: A Putative Iron-Regulatory Hormone Relevant to Hereditary Hemochromatosis and the Anemia of Chronic Disease
2001
Overview
Fleming and Sly comment on the paper by Nicolas et al, in which they present the exciting possibility that a central player in the communication of body iron stores to the intestinal absorptive cells may have been identified. This unlikely player is the hepatic protein hepcidin.
Publisher
National Academy of Sciences,National Acad Sciences,The National Academy of Sciences
Subject
/ Animals
/ Antimicrobial Cationic Peptides - metabolism
/ beta 2-Microglobulin - genetics
/ beta 2-Microglobulin - metabolism
/ Crypts
/ Hemochromatosis - metabolism
/ Histocompatibility Antigens Class I - genetics
/ Histocompatibility Antigens Class I - metabolism
/ Hormones
/ Humans
/ Iron
/ Proteins
/ Receptors, Transferrin - genetics
/ Receptors, Transferrin - metabolism
/ Transcription Factors - genetics
