Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance

by van Ree, Ronald , Tas, Sander W. , de Haas, Aram M. , de Jong, Esther C. , Nagy, Noémi Anna , Geijtenbeek, Teunis B. H. , van Kooyk, Yvette

in activation / Adjuvants / Allergens / Allergies / antigen / Antigens / Autoimmune diseases / Cancer therapies / Cell activation / Cell differentiation / Cytokines / Cytotoxicity / dendritic cell (DC) / Dendritic cells / Dendritic Cells - immunology / Disease / Drug Delivery Systems - methods / Humans / Immune system / Immune Tolerance - immunology / Immunity / Immunity (Disease) / Immunological tolerance / Immunology / Immunotherapy / liposomes / Liposomes - chemistry / Liposomes - immunology / Lymphocytes / nanoparticle / Nanoparticles / Nanoparticles - chemistry / NF-κB protein / Pathogens / Retinoic acid / tolerance / Tumors / Vaccines / Vaccines - chemistry / Vaccines - immunology / Viral infections / Vitamin D3

2021

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance

by van Ree, Ronald , Tas, Sander W. , de Haas, Aram M. , de Jong, Esther C. , Nagy, Noémi Anna , Geijtenbeek, Teunis B. H. , van Kooyk, Yvette

2021

Confirm

Do you wish to request the book?

Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance

by van Ree, Ronald , Tas, Sander W. , de Haas, Aram M. , de Jong, Esther C. , Nagy, Noémi Anna , Geijtenbeek, Teunis B. H. , van Kooyk, Yvette

2021

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Therapeutic Liposomal Vaccines for Dendritic Cell Activation or Tolerance

van Ree, Ronald,

Tas, Sander W.,

de Haas, Aram M.,

de Jong, Esther C.,

Nagy, Noémi Anna,

Geijtenbeek, Teunis B. H.,

van Kooyk, Yvette

2021

Overview

Dendritic cells (DCs) are paramount in initiating and guiding immunity towards a state of activation or tolerance. This bidirectional capacity of DCs sets them at the center stage for treatment of cancer and autoimmune or allergic conditions. Accordingly, many clinical studies use ex vivo DC vaccination as a strategy to boost anti-tumor immunity or to suppress immunity by including vitamin D3, NF-κB inhibitors or retinoic acid to create tolerogenic DCs. As harvesting DCs from patients and differentiating these cells in vitro is a costly and cumbersome process, in vivo targeting of DCs has huge potential as nanoparticulate platforms equipped with activating or tolerogenic adjuvants can modulate DCs in their natural environment. There is a rapid expansion of the choices of nanoparticles and activation- or tolerance-promoting adjuvants for a therapeutic vaccine platform. In this review we highlight the most recent nanomedical approaches aimed at inducing immune activation or tolerance via targeting DCs, together with novel fundamental insights into the mechanisms inherent to fostering anti-tumor or tolerogenic immunity.

Share this book

Add to My Shelf

Publisher

Frontiers Media SA,Frontiers Media S.A

Subject

/ antigen

/ Autoimmune diseases