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Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies
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Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies
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Journal Article
Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies
2017
Overview
Pentacyclic triterpenes are naturally found in a great variety of fruits, vegetables and medicinal plants and are therefore part of the human diet. The beneficial health effects of edible and medicinal plants have partly been associated with their triterpene content, but the in vivo efficacy in humans depends on many factors, including absorption and metabolism. This review presents an overview of in vitro and in vivo studies that were carried out to determine the bioavailability of pentacyclic triterpenes and highlights the efforts that have been performed to improve the dissolution properties and absorption of these compounds. As plant matrices play a critical role in triterpene bioaccessibility, this review covers literature data on the bioavailability of pentacyclic triterpenes ingested either from foods and medicinal plants or in their free form.
Publisher
MDPI AG,MDPI
