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Nationwide measles epidemic in Ukraine: The effect of low vaccine effectiveness
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Journal Article
Nationwide measles epidemic in Ukraine: The effect of low vaccine effectiveness
2008
Overview
The WHO European Region has a measles elimination target for 2010. Between September 2005 and mid-June 2006, more than 50,000 measles cases were reported in Ukraine; many reportedly had received two doses of measles vaccine and over 60% were among persons 15–29 years old. To investigate vaccine effectiveness (VE), a case–control study was undertaken in Dnepropetrovsk region. VE for two doses of measles vaccine was 93.1%, providing insufficient population immunity for measles elimination. An additional dose of measles vaccine for these age-cohorts is required if Ukraine is to achieve measles elimination. Other republics of the former Soviet Union also need to consider a supplemental dose of measles vaccine for older age groups identified epidemiologically to be at increased risk for measles even though individuals may have already received two doses.
Publisher
Elsevier Ltd,Elsevier,Elsevier Limited
Subject
/ Adult
/ Age
/ Biological and medical sciences
/ Data Interpretation, Statistical
/ Fundamental and applied biological sciences. Psychology
/ Gender
/ Humans
/ Measles
/ Measles Vaccine - immunology
/ Students
/ Vaccines
/ Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
/ Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
