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Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature
by
Kurihara, Kanako
, Ogata, Toshiyasu
, Kanda, Takashi
, Ouma, Shinji
, Omoto, Masatoshi
, Tsugawa, Jun
, Aoki, Mikiko
, Tsuboi, Yoshio
in
anti-neutrophil cytoplasmic antibody-negative cases
/ Antibodies
/ Arthritis
/ Asthma
/ Biopsy
/ Blood
/ Cardiovascular disease
/ Case reports
/ eosinophilic granulomatosis with polyangiitis
/ eosinophilic myocarditis
/ Heart failure
/ Immunotherapy
/ Inflammatory diseases
/ Myocarditis
/ Neutrophils
/ Patients
/ Peripheral neuropathy
/ Single Case – General Neurology
/ Single Case − General Neurology
/ Steroids
/ Vein & artery diseases
2021
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Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature
by
Kurihara, Kanako
, Ogata, Toshiyasu
, Kanda, Takashi
, Ouma, Shinji
, Omoto, Masatoshi
, Tsugawa, Jun
, Aoki, Mikiko
, Tsuboi, Yoshio
in
anti-neutrophil cytoplasmic antibody-negative cases
/ Antibodies
/ Arthritis
/ Asthma
/ Biopsy
/ Blood
/ Cardiovascular disease
/ Case reports
/ eosinophilic granulomatosis with polyangiitis
/ eosinophilic myocarditis
/ Heart failure
/ Immunotherapy
/ Inflammatory diseases
/ Myocarditis
/ Neutrophils
/ Patients
/ Peripheral neuropathy
/ Single Case – General Neurology
/ Single Case − General Neurology
/ Steroids
/ Vein & artery diseases
2021
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Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature
by
Kurihara, Kanako
, Ogata, Toshiyasu
, Kanda, Takashi
, Ouma, Shinji
, Omoto, Masatoshi
, Tsugawa, Jun
, Aoki, Mikiko
, Tsuboi, Yoshio
in
anti-neutrophil cytoplasmic antibody-negative cases
/ Antibodies
/ Arthritis
/ Asthma
/ Biopsy
/ Blood
/ Cardiovascular disease
/ Case reports
/ eosinophilic granulomatosis with polyangiitis
/ eosinophilic myocarditis
/ Heart failure
/ Immunotherapy
/ Inflammatory diseases
/ Myocarditis
/ Neutrophils
/ Patients
/ Peripheral neuropathy
/ Single Case – General Neurology
/ Single Case − General Neurology
/ Steroids
/ Vein & artery diseases
2021
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Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature
Journal Article
Eosinophilic Granulomatosis with Polyangiitis Presenting with Myocarditis as an Initial Symptom: A Case Report and Review of the Literature
2021
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Overview
Abstract
A 66-year-old woman with a history of bronchial asthma had shortness of breath and fatigue upon mild exercise. She was diagnosed as congestive heart failure. A blood test showed eosinophilia without the presence of anti-neutrophil cytoplasmic antibody (ANCA), and a myocardial biopsy specimen revealed eosinophilic infiltration in the myocardium. Eosinophilia was improved when she was administered short-term methylprednisolone. After that, she had numbness and pain in her lower limbs with re-elevation of eosinophils. She had dysesthesia and hypalgesia in the distal part of the limbs. Sural nerve biopsy revealed axonal degeneration and thickness of the arterial wall, indicating a diagnosis of eosinophilic granulomatosis with polyangiitis (EGPA). Two courses of steroid pulse therapy were performed, resulting in marked improvement of her sensory symptoms. ANCA-negative EGPA might be associated with myocarditis and peripheral neuropathy. A sufficient immunotherapy should have been considered to prevent rapid progression.
Publisher
S. Karger AG,Karger Publishers
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