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Emerging opportunistic yeast infections
by
Lee, Samuel A
, Díaz, José A
, Miceli, Marisa H
in
azoles
/ beta-Glucans - blood
/ Biological and medical sciences
/ Blood
/ Cancer
/ Candida albicans
/ Candida glabrata
/ Candida krusei
/ Clinical Laboratory Techniques - methods
/ Communicable Diseases, Emerging - diagnosis
/ Communicable Diseases, Emerging - drug therapy
/ Communicable Diseases, Emerging - epidemiology
/ Communicable Diseases, Emerging - microbiology
/ Cryptococcaceae
/ echinocandins
/ Fungi - growth & development
/ Fungi - isolation & purification
/ Fungi - pathogenicity
/ General aspects
/ Geotrichum
/ Hansenula
/ Human immunodeficiency virus
/ Humans
/ Immune status
/ Immunocompromised Host
/ Immunocompromised hosts
/ Incidence
/ Infection
/ Infectious Disease
/ Infectious diseases
/ Invasiveness
/ Malassezia
/ Medical instruments
/ Medical sciences
/ Mycology - methods
/ Mycoses
/ Mycoses - diagnosis
/ Mycoses - drug therapy
/ Mycoses - epidemiology
/ Mycoses - microbiology
/ Opportunistic Infections - diagnosis
/ Opportunistic Infections - drug therapy
/ Opportunistic Infections - epidemiology
/ Opportunistic Infections - microbiology
/ Pathogens
/ Prognosis
/ Rhodotorula
/ Saccharomyces
/ Sepsis
/ Trichosporon
/ Yeasts
2011
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Emerging opportunistic yeast infections
by
Lee, Samuel A
, Díaz, José A
, Miceli, Marisa H
in
azoles
/ beta-Glucans - blood
/ Biological and medical sciences
/ Blood
/ Cancer
/ Candida albicans
/ Candida glabrata
/ Candida krusei
/ Clinical Laboratory Techniques - methods
/ Communicable Diseases, Emerging - diagnosis
/ Communicable Diseases, Emerging - drug therapy
/ Communicable Diseases, Emerging - epidemiology
/ Communicable Diseases, Emerging - microbiology
/ Cryptococcaceae
/ echinocandins
/ Fungi - growth & development
/ Fungi - isolation & purification
/ Fungi - pathogenicity
/ General aspects
/ Geotrichum
/ Hansenula
/ Human immunodeficiency virus
/ Humans
/ Immune status
/ Immunocompromised Host
/ Immunocompromised hosts
/ Incidence
/ Infection
/ Infectious Disease
/ Infectious diseases
/ Invasiveness
/ Malassezia
/ Medical instruments
/ Medical sciences
/ Mycology - methods
/ Mycoses
/ Mycoses - diagnosis
/ Mycoses - drug therapy
/ Mycoses - epidemiology
/ Mycoses - microbiology
/ Opportunistic Infections - diagnosis
/ Opportunistic Infections - drug therapy
/ Opportunistic Infections - epidemiology
/ Opportunistic Infections - microbiology
/ Pathogens
/ Prognosis
/ Rhodotorula
/ Saccharomyces
/ Sepsis
/ Trichosporon
/ Yeasts
2011
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Emerging opportunistic yeast infections
by
Lee, Samuel A
, Díaz, José A
, Miceli, Marisa H
in
azoles
/ beta-Glucans - blood
/ Biological and medical sciences
/ Blood
/ Cancer
/ Candida albicans
/ Candida glabrata
/ Candida krusei
/ Clinical Laboratory Techniques - methods
/ Communicable Diseases, Emerging - diagnosis
/ Communicable Diseases, Emerging - drug therapy
/ Communicable Diseases, Emerging - epidemiology
/ Communicable Diseases, Emerging - microbiology
/ Cryptococcaceae
/ echinocandins
/ Fungi - growth & development
/ Fungi - isolation & purification
/ Fungi - pathogenicity
/ General aspects
/ Geotrichum
/ Hansenula
/ Human immunodeficiency virus
/ Humans
/ Immune status
/ Immunocompromised Host
/ Immunocompromised hosts
/ Incidence
/ Infection
/ Infectious Disease
/ Infectious diseases
/ Invasiveness
/ Malassezia
/ Medical instruments
/ Medical sciences
/ Mycology - methods
/ Mycoses
/ Mycoses - diagnosis
/ Mycoses - drug therapy
/ Mycoses - epidemiology
/ Mycoses - microbiology
/ Opportunistic Infections - diagnosis
/ Opportunistic Infections - drug therapy
/ Opportunistic Infections - epidemiology
/ Opportunistic Infections - microbiology
/ Pathogens
/ Prognosis
/ Rhodotorula
/ Saccharomyces
/ Sepsis
/ Trichosporon
/ Yeasts
2011
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Journal Article
Emerging opportunistic yeast infections
2011
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Overview
A growing population of immunosuppressed patients has resulted in increasingly frequent diagnoses of invasive fungal infections, including those caused by unusual yeasts. The incidence of non-albicans species of
Candida is increasing compared with that of
Candida albicans, and several species, such as
Candida glabrata and
Candida krusei, may be resistant to azole antifungal therapy.
Trichosporon species are the second most common cause of fungaemia in patients with haematological malignant disease and are characterised by resistance to amphotericin and echinocandins and poor prognosis.
Rhodotorula species belong to the family Cryptococcaceae, and are a cause of catheter-related fungaemia, sepsis, and invasive disease in severely immunosuppressed patients. An increasing number of sporadic cases of invasive fungal infections by non-neoformans cryptococci have been reported in immunocompromised hosts, especially for patients with advanced HIV infection or cancer who are undergoing transplant. Other uncommon yeasts that can cause invasive disease in severely immunosuppressed patients include
Geotrichum, Hansenula, Malassezia, and
Saccharomyces. Host immune status is a crucial determinant of the type of invasive fungal infection a patient is at risk for. Diagnosis can be challenging and relies heavily on traditional cultures of blood and other sterile sites, although serum (1,3)-β-D-glucan testing might have an adjunctive role. Although rare yeasts are emerging as opportunistic human pathogens, diagnosis remains challenging and treatment suboptimal.
Publisher
Elsevier Ltd,Lancet Publishing Group,Elsevier Limited
Subject
/ Biological and medical sciences
/ Blood
/ Cancer
/ Clinical Laboratory Techniques - methods
/ Communicable Diseases, Emerging - diagnosis
/ Communicable Diseases, Emerging - drug therapy
/ Communicable Diseases, Emerging - epidemiology
/ Communicable Diseases, Emerging - microbiology
/ Fungi - growth & development
/ Fungi - isolation & purification
/ Human immunodeficiency virus
/ Humans
/ Mycoses
/ Opportunistic Infections - diagnosis
/ Opportunistic Infections - drug therapy
/ Opportunistic Infections - epidemiology
/ Opportunistic Infections - microbiology
/ Sepsis
/ Yeasts
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