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Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia
by
Linde, Margaux B.
, Gerasimenko, Yury P.
, Grahn, Peter J.
, Gad, Parag N.
, Strommen, Jeffrey A.
, Drubach, Dina I.
, Zhao, Kristin D.
, Lee, Kendall H.
, Lopez, Cesar
, Mendez, Aldo A.
, Gill, Megan L.
, Thoreson, Andrew R.
, Edgerton, V. Reggie
, Sayenko, Dimitry G.
, Calvert, Jonathan S.
, Beck, Lisa A.
, Lavrov, Igor A.
, Van Straaten, Meegan G.
in
Adult
/ Body weight
/ Brain stimulation
/ Care and treatment
/ Case reports
/ Colleges & universities
/ Diagnosis
/ Electric Stimulation Therapy - methods
/ Electrical stimuli
/ Electromyography - methods
/ Humans
/ Internal Medicine
/ Male
/ Methods
/ Motor activity
/ Motor task performance
/ Muscle function
/ Muscle, Skeletal - physiopathology
/ Neuromodulation
/ Paralysis
/ Paraplegia
/ Paraplegia - diagnosis
/ Paraplegia - etiology
/ Paraplegia - physiopathology
/ Patient outcomes
/ Physiology
/ Posture - physiology
/ Pyramidal tracts
/ Rehabilitation
/ Rhythms
/ Spinal cord
/ Spinal Cord - physiopathology
/ Spinal cord injuries
/ Spinal Cord Injuries - complications
/ Spinal Cord Injuries - physiopathology
/ Spinal Cord Injuries - therapy
/ Substantia alba
/ Task Performance and Analysis
/ Training
/ Transcranial magnetic stimulation
/ Treatment Outcome
/ Walking - physiology
2017
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Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia
by
Linde, Margaux B.
, Gerasimenko, Yury P.
, Grahn, Peter J.
, Gad, Parag N.
, Strommen, Jeffrey A.
, Drubach, Dina I.
, Zhao, Kristin D.
, Lee, Kendall H.
, Lopez, Cesar
, Mendez, Aldo A.
, Gill, Megan L.
, Thoreson, Andrew R.
, Edgerton, V. Reggie
, Sayenko, Dimitry G.
, Calvert, Jonathan S.
, Beck, Lisa A.
, Lavrov, Igor A.
, Van Straaten, Meegan G.
in
Adult
/ Body weight
/ Brain stimulation
/ Care and treatment
/ Case reports
/ Colleges & universities
/ Diagnosis
/ Electric Stimulation Therapy - methods
/ Electrical stimuli
/ Electromyography - methods
/ Humans
/ Internal Medicine
/ Male
/ Methods
/ Motor activity
/ Motor task performance
/ Muscle function
/ Muscle, Skeletal - physiopathology
/ Neuromodulation
/ Paralysis
/ Paraplegia
/ Paraplegia - diagnosis
/ Paraplegia - etiology
/ Paraplegia - physiopathology
/ Patient outcomes
/ Physiology
/ Posture - physiology
/ Pyramidal tracts
/ Rehabilitation
/ Rhythms
/ Spinal cord
/ Spinal Cord - physiopathology
/ Spinal cord injuries
/ Spinal Cord Injuries - complications
/ Spinal Cord Injuries - physiopathology
/ Spinal Cord Injuries - therapy
/ Substantia alba
/ Task Performance and Analysis
/ Training
/ Transcranial magnetic stimulation
/ Treatment Outcome
/ Walking - physiology
2017
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Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia
by
Linde, Margaux B.
, Gerasimenko, Yury P.
, Grahn, Peter J.
, Gad, Parag N.
, Strommen, Jeffrey A.
, Drubach, Dina I.
, Zhao, Kristin D.
, Lee, Kendall H.
, Lopez, Cesar
, Mendez, Aldo A.
, Gill, Megan L.
, Thoreson, Andrew R.
, Edgerton, V. Reggie
, Sayenko, Dimitry G.
, Calvert, Jonathan S.
, Beck, Lisa A.
, Lavrov, Igor A.
, Van Straaten, Meegan G.
in
Adult
/ Body weight
/ Brain stimulation
/ Care and treatment
/ Case reports
/ Colleges & universities
/ Diagnosis
/ Electric Stimulation Therapy - methods
/ Electrical stimuli
/ Electromyography - methods
/ Humans
/ Internal Medicine
/ Male
/ Methods
/ Motor activity
/ Motor task performance
/ Muscle function
/ Muscle, Skeletal - physiopathology
/ Neuromodulation
/ Paralysis
/ Paraplegia
/ Paraplegia - diagnosis
/ Paraplegia - etiology
/ Paraplegia - physiopathology
/ Patient outcomes
/ Physiology
/ Posture - physiology
/ Pyramidal tracts
/ Rehabilitation
/ Rhythms
/ Spinal cord
/ Spinal Cord - physiopathology
/ Spinal cord injuries
/ Spinal Cord Injuries - complications
/ Spinal Cord Injuries - physiopathology
/ Spinal Cord Injuries - therapy
/ Substantia alba
/ Task Performance and Analysis
/ Training
/ Transcranial magnetic stimulation
/ Treatment Outcome
/ Walking - physiology
2017
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Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia
Journal Article
Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia
2017
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Overview
We report a case of chronic traumatic paraplegia in which epidural electrical stimulation (EES) of the lumbosacral spinal cord enabled (1) volitional control of task-specific muscle activity, (2) volitional control of rhythmic muscle activity to produce steplike movements while side-lying, (3) independent standing, and (4) while in a vertical position with body weight partially supported, voluntary control of steplike movements and rhythmic muscle activity. This is the first time that the application of EES enabled all of these tasks in the same patient within the first 2 weeks (8 stimulation sessions total) of EES therapy.
Publisher
Elsevier Inc,Frontline Medical Communications Inc,Elsevier Limited
Subject
/ Electric Stimulation Therapy - methods
/ Humans
/ Male
/ Methods
/ Muscle, Skeletal - physiopathology
/ Paraplegia - physiopathology
/ Rhythms
/ Spinal Cord - physiopathology
/ Spinal Cord Injuries - complications
/ Spinal Cord Injuries - physiopathology
/ Spinal Cord Injuries - therapy
/ Task Performance and Analysis
/ Training
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