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Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti- tumor effects in the digestive system
by
Kun ZOU Zhao LI Yong ZHANG Hao-yue ZHANG Bo LI Wei-liang ZHU Ji-ye SHI Qi JIA Yi-ming LI
in
Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents - therapeutic use
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Berberine - analogs & derivatives
/ Berberine - pharmacology
/ Berberine - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Digestive System - drug effects
/ Humans
/ Immunology
/ Internal Medicine
/ Medical Microbiology
/ Pharmacology/Toxicology
/ Review
/ Structure-Activity Relationship
/ Vaccine
/ 天然产物
/ 小檗碱
/ 慢性炎症
/ 抗炎活性
/ 抗肿瘤作用
/ 治疗效果
/ 消化系统
/ 衍生物
2017
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Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti- tumor effects in the digestive system
by
Kun ZOU Zhao LI Yong ZHANG Hao-yue ZHANG Bo LI Wei-liang ZHU Ji-ye SHI Qi JIA Yi-ming LI
in
Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents - therapeutic use
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Berberine - analogs & derivatives
/ Berberine - pharmacology
/ Berberine - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Digestive System - drug effects
/ Humans
/ Immunology
/ Internal Medicine
/ Medical Microbiology
/ Pharmacology/Toxicology
/ Review
/ Structure-Activity Relationship
/ Vaccine
/ 天然产物
/ 小檗碱
/ 慢性炎症
/ 抗炎活性
/ 抗肿瘤作用
/ 治疗效果
/ 消化系统
/ 衍生物
2017
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Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti- tumor effects in the digestive system
by
Kun ZOU Zhao LI Yong ZHANG Hao-yue ZHANG Bo LI Wei-liang ZHU Ji-ye SHI Qi JIA Yi-ming LI
in
Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents - therapeutic use
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Berberine - analogs & derivatives
/ Berberine - pharmacology
/ Berberine - therapeutic use
/ Biomedical and Life Sciences
/ Biomedicine
/ Digestive System - drug effects
/ Humans
/ Immunology
/ Internal Medicine
/ Medical Microbiology
/ Pharmacology/Toxicology
/ Review
/ Structure-Activity Relationship
/ Vaccine
/ 天然产物
/ 小檗碱
/ 慢性炎症
/ 抗炎活性
/ 抗肿瘤作用
/ 治疗效果
/ 消化系统
/ 衍生物
2017
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Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti- tumor effects in the digestive system
Journal Article
Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti- tumor effects in the digestive system
2017
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Overview
It has been widely recognized that inflammation, particularly chronic inflammation, can increase the risk of cancer and that the simultaneous treatment of inflammation and cancer may produce excellent therapeutic effects. Berberine, an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic with a long history. Over the past decade, many reports have demonstrated that this natural product and its derivatives have high activity against both cancer and inflammation In this review, we sqmmarize the advances in studing berberine and its derivatives as anti-inflammatory and anti-tumor agents in the digestive system; we also discuss their structure-activity relationship. These data should be useful for the development of this natural product as novel anticancer drugs with anti-inflammation activity.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
Anti-Inflammatory Agents - pharmacology
/ Anti-Inflammatory Agents - therapeutic use
/ Anti-Inflammatory Agents, Non-Steroidal - pharmacology
/ Antineoplastic Agents - pharmacology
/ Antineoplastic Agents - therapeutic use
/ Berberine - analogs & derivatives
/ Biomedical and Life Sciences
/ Digestive System - drug effects
/ Humans
/ Review
/ Structure-Activity Relationship
/ Vaccine
/ 天然产物
/ 小檗碱
/ 慢性炎症
/ 抗炎活性
/ 抗肿瘤作用
/ 治疗效果
/ 消化系统
/ 衍生物
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