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Human Papillomavirus and Diseases of the Upper Airway: Head and Neck Cancer and Respiratory Papillomatosis

by Schwartz, Steve , Castellsagué, Xavier , Steinberg, Bettie M , Gillison, Maura L , Chaturvedi, Anil , Alemany, Laia , Snijders, Peter J.F

in Allergy and Immunology / Benign / carcinogenicity / case-control studies / Causality / Epidemiology / gene expression / head / Head and neck cancer / Head and Neck Neoplasms - epidemiology / Head and Neck Neoplasms - virology / HPV / Human papillomavirus / Human papillomavirus 16 / Humans / immunohistochemistry / in situ hybridization / larynx / messenger RNA / mouth / nasopharynx / neck / oropharyngeal neoplasms / Oropharynx / papilloma / Papillomatosis / Papillomaviridae / Papillomaviridae - classification / Papillomaviridae - isolation & purification / Papillomaviridae - pathogenicity / Papillomavirus Infections - complications / Papillomavirus Infections - epidemiology / Papillomavirus Infections - virology / patients / phenotype / prognosis / Respiratory Tract Infections - complications / Respiratory Tract Infections - epidemiology / Respiratory Tract Infections - virology / vaccination / vaccines

2012

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Human Papillomavirus and Diseases of the Upper Airway: Head and Neck Cancer and Respiratory Papillomatosis

by Schwartz, Steve , Castellsagué, Xavier , Steinberg, Bettie M , Gillison, Maura L , Chaturvedi, Anil , Alemany, Laia , Snijders, Peter J.F

2012

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Human Papillomavirus and Diseases of the Upper Airway: Head and Neck Cancer and Respiratory Papillomatosis

by Schwartz, Steve , Castellsagué, Xavier , Steinberg, Bettie M , Gillison, Maura L , Chaturvedi, Anil , Alemany, Laia , Snijders, Peter J.F

2012

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Journal Article

Human Papillomavirus and Diseases of the Upper Airway: Head and Neck Cancer and Respiratory Papillomatosis

Schwartz, Steve,

Castellsagué, Xavier,

Steinberg, Bettie M,

Gillison, Maura L,

Chaturvedi, Anil,

Alemany, Laia,

Snijders, Peter J.F

2012

Overview

Highlights ► HPV16 is necessary for initiation/malignant phenotype of some oropharynx cancers. ► Infection by HPV16 is associated with elevated odds of oropharynx cancer. ► Tumor HPV status is an important prognostic factor for oropharynx cancer. ► HPV-positive oropharynx cancer incidence is increasing in developed countries. ► Respiratory papillomatosis is caused by peripartum/sexual transmission of HPV6/11.

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Publisher

Elsevier Ltd

Subject

Allergy and Immunology

/ Benign

/ carcinogenicity

/ case-control studies

/ Causality

/ Epidemiology

/ gene expression