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Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment
by
Lucisano, Marília Pacífico
, Messora Michel Reis
, Feres Magda
, da Silva Raquel Assed Bezerra
, Novaes Júnior Arthur Belém
, Shirozaki Mariana Umekita
, da Silva Léa Assed Bezerra
, Romano, Fábio Lourenço
, De Rossi Andiara
in
Biofilms
/ Bleeding
/ Gingiva
/ IL-1β
/ Immunology
/ Neutrophil collagenase
/ Orthodontics
/ Patients
/ Plaque index
/ Statistical analysis
/ Tumor necrosis factor-α
2020
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Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment
by
Lucisano, Marília Pacífico
, Messora Michel Reis
, Feres Magda
, da Silva Raquel Assed Bezerra
, Novaes Júnior Arthur Belém
, Shirozaki Mariana Umekita
, da Silva Léa Assed Bezerra
, Romano, Fábio Lourenço
, De Rossi Andiara
in
Biofilms
/ Bleeding
/ Gingiva
/ IL-1β
/ Immunology
/ Neutrophil collagenase
/ Orthodontics
/ Patients
/ Plaque index
/ Statistical analysis
/ Tumor necrosis factor-α
2020
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While trying to remove the title from your shelf something went wrong :( Kindly try again later!
Do you wish to request the book?
Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment
by
Lucisano, Marília Pacífico
, Messora Michel Reis
, Feres Magda
, da Silva Raquel Assed Bezerra
, Novaes Júnior Arthur Belém
, Shirozaki Mariana Umekita
, da Silva Léa Assed Bezerra
, Romano, Fábio Lourenço
, De Rossi Andiara
in
Biofilms
/ Bleeding
/ Gingiva
/ IL-1β
/ Immunology
/ Neutrophil collagenase
/ Orthodontics
/ Patients
/ Plaque index
/ Statistical analysis
/ Tumor necrosis factor-α
2020
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Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment
Journal Article
Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment
2020
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Overview
BackgroundThe objective was to analyze clinical, microbiological, and immunological periodontal parameters in patients in corrective orthodontic treatment.Materials and methodsTwenty-eight patients were selected. Plaque index (PI), bleeding on probing (BOP), width of keratinized gingiva, levels of 40 bacterial species, and of 3 cytokines (IL-1β, MMP-8, and TNF-α) in gingival crevicular fluid (GCF) were evaluated at T0, before orthodontic treatment; T1, 6 months; and T2, 12 months post-treatment. Non-parametric, Friedman, Wilcoxon, ANOVA, and Spearman correlation coefficient tests were used for statistical analyses, with the significance level of 5%.ResultsNo significant difference was found for the width of keratinized gingiva, but PI presented a significant increase at T1 and T2 (p < 0.05) when compared with T0. The percentage of sites with BOP increased significantly from T0 to T1 (p < 0.05); however, at T2, the values decreased and did not differ anymore from T0 (p > 0.05). In the microbiological analysis, red complex pathogens were in significantly greater proportions in T2 compared with T0 (p < 0.05). There was no statistically significant difference in the cytokine levels between the periods but there was a positive correlation between BOP and IL-1β (r = 0.49 p = .01) and TNF-α (r = 0.39 and p = .05).ConclusionIn conclusion, corrective orthodontic treatment caused clinical periodontal alterations regarding biofilm accumulation and gingival bleeding, with alteration of periodontopathogens.
Publisher
Springer Nature B.V
Subject
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