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Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan
by
Komatsu, Shuhei
, Otsuji, Eigo
in
biomarker
/ Biomarkers
/ Biopsy
/ Cancer therapies
/ Gastric cancer
/ Gastric Cancer Treatment Guidelines
/ Immune checkpoint inhibitors
/ Japanese Classification of Gastric Carcinoma
/ MicroRNAs
/ PD‐1 immune checkpoint inhibitor
/ Review
2019
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Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan
by
Komatsu, Shuhei
, Otsuji, Eigo
in
biomarker
/ Biomarkers
/ Biopsy
/ Cancer therapies
/ Gastric cancer
/ Gastric Cancer Treatment Guidelines
/ Immune checkpoint inhibitors
/ Japanese Classification of Gastric Carcinoma
/ MicroRNAs
/ PD‐1 immune checkpoint inhibitor
/ Review
2019
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Do you wish to request the book?
Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan
by
Komatsu, Shuhei
, Otsuji, Eigo
in
biomarker
/ Biomarkers
/ Biopsy
/ Cancer therapies
/ Gastric cancer
/ Gastric Cancer Treatment Guidelines
/ Immune checkpoint inhibitors
/ Japanese Classification of Gastric Carcinoma
/ MicroRNAs
/ PD‐1 immune checkpoint inhibitor
/ Review
2019
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Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan
Journal Article
Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan
2019
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Overview
Recent developments in diagnostic technology, accumulated clinical effort and established evidence have boosted early detection and drastically improved early and long‐term outcomes of gastric cancer. However, gastric cancer continues to be one of the most aggressive and life‐threatening malignancies among all cancers and is a global health problem. Between January 2017 and December 2018, various fascinating reports of managements and research were published, including the new 15th Japanese Classification of Gastric Carcinoma reflecting the 8th American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumor, node and metastasis (TNM) classification (October 2017) and the new Gastric Cancer Treatment Guidelines version 5 (January 2018). Moreover, pivotal molecular features of gastric cancer were clarified by the worldwide cancer genome project, and various treatment targets and biomarkers such as circulating DNAs and microRNAs were detected. Novel treatment options using programmed cell death protein 1 immune checkpoint inhibitors have been started. In this review, we summarize the recent topics of classification, guidelines, and clinical and basic research in order to bring new insights to gastric cancer treatment. The greatest change in the 15th edition of JGCA staging systems for gastric cancer was the separate inclusion of N3a and N3b. In the new 15th JGCA classification, T1–T3 disease was upstaged with N3b, T4aN3a was downstaged from IIIC to IIIB and T4bN0 and T4aN2 were downstaged from IIIB to IIIA.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley
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