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Lower oxygen saturation with higher rates of norepinephrine in bone fractures of polytrauma patients: a pilot study
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Lower oxygen saturation with higher rates of norepinephrine in bone fractures of polytrauma patients: a pilot study
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Journal Article
Lower oxygen saturation with higher rates of norepinephrine in bone fractures of polytrauma patients: a pilot study
2023
Overview
In a pilot trial, we used the laser-Doppler device ‘Oxygen to see’ (O2C, LEA Medizintechnik, Winchesterstr. 2, D-35394 Gießen, Germany) to measure SO2, haemoglobin (Hb), and blood flow (BF) in 3, 10, and 14/16 mm depth in four tibial and clavicle fractures of three patients with multiple injuries who received NE. In 3 mm, up to 14.7% of the variability could be explained by MAP alone, and in 14/16 mm, up to 13.5% by NE alone. [...]only NE and not MAP had an effect on SO2 in 14/16 mm depth inside the fractures. Effect of early use of noradrenaline on in-hospital mortality in haemorrhagic shock after major trauma: a propensity-score analysis.
