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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

by Kröger, N , Passweg, J R , Farge-Bancel, D , Mohty, M , Baldomero, H , Kuball, J , Dreger, P , Bonini, C , Nagler, A , Bader, P , Dufour, C , Gennery, A , Lanza, F , Sureda, A , Duarte, R F , Cesaro, S

in 692/699/1541/1990 / 692/700/459 / Amyloidosis - therapy / Anemia, Aplastic - therapy / Bone marrow / Cell Biology / Cord Blood Stem Cell Transplantation - statistics & numerical data / Europe / Fetal blood / Hematology / Hematopoietic stem cell transplantation / Hematopoietic Stem Cell Transplantation - methods / Hematopoietic Stem Cell Transplantation - statistics & numerical data / Hematopoietic Stem Cell Transplantation - trends / Hematopoietic Stem Cell Transplantation - utilization / Humans / Internal Medicine / Medicine / Medicine & Public Health / Neoplasms - therapy / Original / original-article / Patient Care Team - statistics & numerical data / Patient Care Team - trends / Public Health / Stem cell transplantation / Stem Cells / Surveys and Questionnaires / Tissue Donors - statistics & numerical data / Transplantation, Autologous / Transplantation, Haploidentical / Transplantation, Homologous

2016

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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

2016

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Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

2016

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Journal Article

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

Kröger, N,

Passweg, J R,

Farge-Bancel, D,

Mohty, M,

Baldomero, H,

Kuball, J,

Dreger, P,

Bonini, C,

Nagler, A,

Bader, P,

Dufour, C,

Gennery, A,

Lanza, F,

Sureda, A,

Duarte, R F,

Cesaro, S

2016

Overview

A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.

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Publisher

Nature Publishing Group UK,Nature Publishing Group

Subject

692/699/1541/1990

/ 692/700/459

/ Amyloidosis - therapy

/ Anemia, Aplastic - therapy

/ Bone marrow

/ Cell Biology

/ Cord Blood Stem Cell Transplantation - statistics & numerical data