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A case study on co-exposure to a mixture of organic solvents in a Tunisian adhesive-producing company
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A case study on co-exposure to a mixture of organic solvents in a Tunisian adhesive-producing company
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Journal Article
A case study on co-exposure to a mixture of organic solvents in a Tunisian adhesive-producing company
2011
Overview
Objectives
to assess environmental and biological monitoring of exposure to organic solvents in a glue-manufacturing company in Sfax, Tunisia.
Methods
Exposure of volunteer workers, in the solvented glue-work-stations, in the control laboratory and in the storage rooms of the finished products, was assessed through indoor-air and urine measurements. Informed consent of the workers was obtained.
Results and discussion
The exposure indexes were found with high values in the solvented workshop as well as in the control laboratory and were respectively, 8.40 and 3.12. These indexes were also correlated with hexane and toluene indoor air concentrations. As to urine, the obtained results for the 2,5-hexandione and hippuric acid, metabolites of hexane and toluene, respectively, were in accord with the indoor-air measurements, with an average of 0.46 mg/l and 1240 mg/g of creatinine.
Conclusion
This study assessed for the first time biological exposure to organic solvents used in Tunisian adhesive industries. Although values are likely to underestimate true exposure levels, some figures exceed European and American occupational exposure guidelines.
Publisher
BioMed Central,BioMed Central Ltd,BMC
