Journal Article

A new occlusive patch test system comparable to IQ and Finn chambers

Salvi, Anjali, Mohile, RashmikantB, Vaidya, AshleshaD, Joshi, RajivS, Sajun Merchant, ShaziyaZ

2014

Overview

A good patch test system should have good adhesion and contact, and minimal leakage; Finn and IQ patch test system have these properties but are expensive. To develop a new cost-effective occlusive patch test system that had good contact with the skin and was non-irritant. The system (designated Chamber X) was fabricated using a semi-permeable tape and a flexible virgin plastic chamber. Chamber X was developed by (i) selecting adhesive tape based on its non irritancy and adhesive potential (ii) testing plastic chamber material for its skin irritancy (iii) testing the assembled system against Finn, IQ and locally available chambers for irritancy, contact, leakage and occlusivity. Chamber X showed better occlusion than IQ, Finn and locally available chambers and was comparable to, (P > 0.05) IQ and Finn in terms of irritancy, contact and leakage. The results demonstrate that the Chamber X offers a cost effective patch test system comparable to IQ and Finn chambers in terms of safety, adhesion, leakage and occlusivity.

• Publisher: Medknow Publications and Media Pvt. Ltd,Scientific Scholar
• Subject: Allergens - administration & dosage / Allergens - metabolism / Comparative analysis / Contact dermatitis / Dermatitis, Allergic Contact - diagnosis / Dermatitis, Allergic Contact - metabolism / Dermatology / Diagnosis / Diagnostic tests / Equipment and supplies / Equipment Design - standards / Equipment Design - trends / Humans / Irritants - administration & dosage / Irritants - metabolism / Methods / Patch Tests - standards / Patch Tests - trends / Skin - metabolism / Skin tests