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硬膜外麻醉下持续靶控输注丙泊酚的镇静效果
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Journal Article
硬膜外麻醉下持续靶控输注丙泊酚的镇静效果
2003
Overview
目的 评价丙泊酚靶控输注(TCI)在硬膜外阻滞麻醉不同镇静分级时的脑电双频谱指数(BIS)与生命体征变化。方法 择期硬膜外麻醉下行中下腹部手术的53例患者，采用自身对照，比较在不同Ramsay分级时，丙泊酚靶控输注的效应部位浓度(ESC)与BIS值生命体征变化。结果 在Ramsay 4级时的ESC为(1．66±0．16)mg·L^-1，BIS为78.5±4．6，生命体征平稳，其HR、MAP、RRS、SPO2与Ramsay 2级比较无差异(P>0．05)；与Ramsay5级、6级比较差异有显著性(P<0．01)。结论 随着丙泊酚靶控输注的效应部位浓度的增加，BIS值呈计量相关性下降并能指导镇静分级。在硬膜外阻滞麻醉下Ramsay镇静4级时较为适宜，生命体征平稳，并发症少。
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