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Mitochondrial Network Size Scaling in Budding Yeast
by
Rafelski, Susanne M.
, Fung, Jennifer C.
, da F. Costa, Luciano
, Viana, Matheus P.
, Chan, Yee-Hung M.
, Li, Hao
, Thorn, Kurt S.
, Marshall, Wallace F.
, Zhang, Yi
, Yam, Phoebe
in
Analytical, structural and metabolic biochemistry
/ Biological and medical sciences
/ Budding
/ Cell growth
/ Cells
/ Cellular biology
/ Cellular metabolism
/ Fundamental and applied biological sciences. Psychology
/ G1 Phase
/ Genetics
/ Life span
/ Microscopy, Confocal
/ Mitochondria
/ Mitochondria - metabolism
/ Mitochondria - ultrastructure
/ Mitochondrial genes
/ Mitochondrial Size
/ Molecular and cellular biology
/ Mother cells
/ Mothers
/ quantitative analysis
/ rab GTP-Binding Proteins - genetics
/ rab GTP-Binding Proteins - metabolism
/ Saccharomyces cerevisiae
/ Saccharomyces cerevisiae - cytology
/ Saccharomyces cerevisiae - growth & development
/ Saccharomyces cerevisiae - ultrastructure
/ Saccharomyces cerevisiae Proteins - genetics
/ Saccharomyces cerevisiae Proteins - metabolism
/ Saccharomycetales
/ Yeast
/ Yeasts
2012
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Mitochondrial Network Size Scaling in Budding Yeast
by
Rafelski, Susanne M.
, Fung, Jennifer C.
, da F. Costa, Luciano
, Viana, Matheus P.
, Chan, Yee-Hung M.
, Li, Hao
, Thorn, Kurt S.
, Marshall, Wallace F.
, Zhang, Yi
, Yam, Phoebe
in
Analytical, structural and metabolic biochemistry
/ Biological and medical sciences
/ Budding
/ Cell growth
/ Cells
/ Cellular biology
/ Cellular metabolism
/ Fundamental and applied biological sciences. Psychology
/ G1 Phase
/ Genetics
/ Life span
/ Microscopy, Confocal
/ Mitochondria
/ Mitochondria - metabolism
/ Mitochondria - ultrastructure
/ Mitochondrial genes
/ Mitochondrial Size
/ Molecular and cellular biology
/ Mother cells
/ Mothers
/ quantitative analysis
/ rab GTP-Binding Proteins - genetics
/ rab GTP-Binding Proteins - metabolism
/ Saccharomyces cerevisiae
/ Saccharomyces cerevisiae - cytology
/ Saccharomyces cerevisiae - growth & development
/ Saccharomyces cerevisiae - ultrastructure
/ Saccharomyces cerevisiae Proteins - genetics
/ Saccharomyces cerevisiae Proteins - metabolism
/ Saccharomycetales
/ Yeast
/ Yeasts
2012
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Mitochondrial Network Size Scaling in Budding Yeast
by
Rafelski, Susanne M.
, Fung, Jennifer C.
, da F. Costa, Luciano
, Viana, Matheus P.
, Chan, Yee-Hung M.
, Li, Hao
, Thorn, Kurt S.
, Marshall, Wallace F.
, Zhang, Yi
, Yam, Phoebe
in
Analytical, structural and metabolic biochemistry
/ Biological and medical sciences
/ Budding
/ Cell growth
/ Cells
/ Cellular biology
/ Cellular metabolism
/ Fundamental and applied biological sciences. Psychology
/ G1 Phase
/ Genetics
/ Life span
/ Microscopy, Confocal
/ Mitochondria
/ Mitochondria - metabolism
/ Mitochondria - ultrastructure
/ Mitochondrial genes
/ Mitochondrial Size
/ Molecular and cellular biology
/ Mother cells
/ Mothers
/ quantitative analysis
/ rab GTP-Binding Proteins - genetics
/ rab GTP-Binding Proteins - metabolism
/ Saccharomyces cerevisiae
/ Saccharomyces cerevisiae - cytology
/ Saccharomyces cerevisiae - growth & development
/ Saccharomyces cerevisiae - ultrastructure
/ Saccharomyces cerevisiae Proteins - genetics
/ Saccharomyces cerevisiae Proteins - metabolism
/ Saccharomycetales
/ Yeast
/ Yeasts
2012
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Journal Article
Mitochondrial Network Size Scaling in Budding Yeast
2012
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Overview
Mitochondria must grow with the growing cell to ensure proper cellular physiology and inheritance upon division. We measured the physical size of mitochondrial networks in budding yeast and found that mitochondrial network size increased with increasing cell size and that this scaling relation occurred primarily in the bud. The mitochondria-to-cell size ratio continually decreased in aging mothers over successive generations. However, regardless of the mother's age or mitochondrial content, all buds attained the same average ratio. Thus, yeast populations achieve a stable scaling relation between mitochondrial content and cell size despite asymmetry in inheritance.
Publisher
American Association for the Advancement of Science,The American Association for the Advancement of Science
Subject
Analytical, structural and metabolic biochemistry
/ Biological and medical sciences
/ Budding
/ Cells
/ Fundamental and applied biological sciences. Psychology
/ G1 Phase
/ Genetics
/ Mitochondria - ultrastructure
/ Molecular and cellular biology
/ Mothers
/ rab GTP-Binding Proteins - genetics
/ rab GTP-Binding Proteins - metabolism
/ Saccharomyces cerevisiae - cytology
/ Saccharomyces cerevisiae - growth & development
/ Saccharomyces cerevisiae - ultrastructure
/ Saccharomyces cerevisiae Proteins - genetics
/ Saccharomyces cerevisiae Proteins - metabolism
/ Yeast
/ Yeasts
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