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Skin Microbiome: An Actor in the Pathogenesis of Psoriasis
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Skin Microbiome: An Actor in the Pathogenesis of Psoriasis
Skin Microbiome: An Actor in the Pathogenesis of Psoriasis
Journal Article

Skin Microbiome: An Actor in the Pathogenesis of Psoriasis

2018
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Overview
INTRODUCTION Psoriasis is characterized by raised, scaly, well-demarcated, erythematous oval plaques. Although studies have revealed that disruption of immune tolerance and excessive production of inflammatory factors play important roles in the pathogenesis of psoriasis, the exact mechanism is still not clear Previous studies have shown that the concordance rate of monozygotic twins with psoriasis is greater than that of dizygotic twins, with genetic thctors underpinning 66-90% of the variation in risk of developing psoriasis.