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Microbiota and reproducibility of rodent models
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Microbiota and reproducibility of rodent models
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Journal Article
Microbiota and reproducibility of rodent models
2017
Overview
The gut microbiota (GM) plays a critical role in human health and disease. Likewise, it is becoming increasingly evident that changes or disruptions to the GM can have significant effects on animal models and their expressed phenotypes, adding a complex and important variable into basic research and preclinical studies. In this article, we review some of the most common sources of GM variability in rodent models, and discuss measures to address this variability for improved reproducibility.
Publisher
Nature Publishing Group US,Nature Publishing Group
