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血液透析患者不宁腿综合征相关影响因素分析
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血液透析患者不宁腿综合征相关影响因素分析
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Journal Article
血液透析患者不宁腿综合征相关影响因素分析
2018
Overview
目的调查血液透析患者不宁腿综合征发病率并筛查其相关危险因素。方法共220例维持性血液透析患者和40例慢性肾脏病患者,采用国际不宁腿综合征研究组评价量表（IRLS）评价不宁腿综合征严重程度,Beck抑郁量表（BDI）评价抑郁症状,Epworth嗜睡量表评价白天过度嗜睡,失眠严重程度指数（ISI）评价失眠程度。采用单因素和多因素前进法Logistic回归分析筛查血液透析患者发生不宁腿综合征的相关危险因素。结果血液透析组病程（Z=-9.837,P=0.000）、血清铁蛋白（t=2.847,P=0.005）、合并不宁腿综合征比例（χ~2=10.918,P=0.001）、应用镇静催眠药比例（χ~2=7.669,P=0.006）、IRLS评分（t=2.322,P=0.020）和ISI评分（Z=4.117,P=0.001）均高于对照组。单因素和多因素前进法Logistic回归分析显示,糖尿病（OR=3.387,95%CI：1.538~7.461;P=0.002）、BDI评分〉9分（OR=2.643,95%CI：1.457~4.795;P=0.001）和ISI评分〉7分（OR=3.542,95%CI：1.939~6.468;P=0.000）是血液透析患者发生不宁腿综合征的独立危险因素。结论血液透析患者不宁腿综合征和失眠发病率较高,不宁腿综合征与失眠密切相关,抑郁症状在其中发挥重要作用。
Publisher
100048 北京,解放军总医院第一附属医院肾内科
Subject
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