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Investigation of the relationship between helicobacter pylori positivity and colon polyps in simultaneous oesophagogastroduodenoscopy and colonoscopy procedures
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Investigation of the relationship between helicobacter pylori positivity and colon polyps in simultaneous oesophagogastroduodenoscopy and colonoscopy procedures
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Investigation of the relationship between helicobacter pylori positivity and colon polyps in simultaneous oesophagogastroduodenoscopy and colonoscopy procedures
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Journal Article
Investigation of the relationship between helicobacter pylori positivity and colon polyps in simultaneous oesophagogastroduodenoscopy and colonoscopy procedures
2026
Overview
Abstract
Introduction:
Colorectal polyps evolve into colorectal cancer with genetic mutations. Helicobacter pylori (HP) infection, which is classified as carcinogen, is thought to affect 50% of the world population.
Patients and Methods:
Retrospectively, demographic data, HP positivity status, the size, location and number of polyps in patients over 18 years of age who underwent simultaneous sedated oesophagogastroduodenoscopy and colonoscopy procedures between January 2023 and December 2023 were analysed and documented through file records.
Results:
One hundred and sixteen patients with polyps in the colon and who underwent polypectomy were analysed. HP histology was positive in 50% of cases with colon polyps. No difference was observed in age, gender, number of polyps, polyp size, polyp type and polyp localisation between patients with HP and patients without HP. Colon polyps in patients with tubular adenoma were more common in the transverse colon (P = 0.035). However, no difference was observed regarding HP histology. In patients with hyperplastic polyps, the proportion of patients with a polyp size above 1 cm was higher and those with a polyp size below 0.5 cm was lower (P = 0.029). However, no difference was observed regarding polyp localisation and HP.
Conclusion:
Although HP may be effective on colon polyps due to its effect on virulence factors and gastrointestinal hormones, current literature cannot clearly address this question and the relationship between HP histology and colon polyps is still controversial. In the present study, no significant results were found between demographic data and subtypes of polyps.
