Journal Article

Vapoenucleation of the prostate using a high-power thulium laser: a one-year follow-up study

Chang, Yen-Hwa, Chang, Ching-Hsin, Lin, Tzu-Ping, Huang, William JS, Chen, Kuang-Kuo, Lin, Alex TL

2015

Overview

Background Prostate vaporization and enucleation is a novel treatment option for bladder outlet obstruction caused by benign prostate enlargement. This surgical technique, however, has not yet been standardized. We present our findings of using a high-power thulium laser to accomplish vapoenucleation of the prostate (ThuVEP). Methods We prospectively collected and analyzed data from 29 patients who underwent ThuVEP between August 2010 and May 2012. The control group included 30 patients who underwent traditional transurethral resection of the prostate (TURP). Operative variables, patient profiles, preoperative and postoperative urine flow rates, prostate volume (measured using transrectal ultrasonography), and the international prostate symptom score (IPSS) were recorded and analyzed using a two-tailed Student’s t -test and analysis of variance. Results The ages (mean ± SD) of the patients were 76.1 ± 9.4 and 72.6 ± 7.4 years ( p  = 0.28) in the ThuVEP and TURP groups, respectively. The average urinary flow rates before and 12 months after the operation (volume/maximum flow/average flow) were 243.3/10.5/5.0 and 302.8/17.6/9.4 (in mL, mL/s, mL/s, respectively) in the ThuVEP group and 247.2/10.8/4.6 and 369.9/20.8/12.0, respectively, in the TURP group. Preoperative and postoperative IPSSs were 17.1 ± 5.0 and 6.5 ± 3.8, respectively, in the ThuVEP group and 18.2 ± 4.5 and 6.2 ± 3.3, respectively, in the TURP group. The mean ratio of the estimated postoperative residual prostate volume to the preoperative total volume was 0.47 ( p  = 0.449) in both groups. The overall complication rate was 20.7% in the ThuVEP group and 30.0% in the TURP group. Conclusions One year of follow-up showed that ThuVEP and TURP effectively alleviated subjective and objective voiding symptoms with a low rate of complications. Thus, vapoenucleation using a high-power laser is feasible in elderly patients. Trial registration ISRCTN registry with study ID ISRCTN52339705 . Date assigned: 06/03/2015.

• Publisher: BioMed Central,BioMed Central Ltd
• Subject: Age Factors / Aged / Aged, 80 and over / Analysis / Endourology and technology / Follow-Up Studies / Humans / Internal Medicine / Laser Therapy - methods / Lasers in medicine / Lasers, Solid-State - therapeutic use / Male / Medicine / Medicine & Public Health / Prospective Studies / Prostatic Hyperplasia - complications / Prostatic Hyperplasia - diagnosis / Prostatic Hyperplasia - surgery / Research Article / Risk Assessment / Severity of Illness Index / Sex Factors / Thulium / Time Factors / Transurethral Resection of Prostate - methods / Treatment Outcome / Urinary Bladder Neck Obstruction - etiology / Urinary Bladder Neck Obstruction - physiopathology / Urinary Bladder Neck Obstruction - surgery / Urinary Retention - etiology / Urinary Retention - physiopathology / Urinary Retention - surgery / Urology