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Journal Article
ST段抬高型急性心肌梗死患者猝死预警指标Tp-e/QT比值的应用价值
2010
Overview
目的检测急性ST段抬高型心肌梗死（STEMI）患者的Tp-e/QT比值,并探讨其发生猝死的临床意义。方法对120例急性STEMI患者（心肌梗死组）、119例健康成人（对照组）分别测量其入院24h内的第1份心电图QTc、QTd、、Tp-e,并计算Tp-e/QT比值,分析其与恶性室性心律失常发生的关系。结果与健康组相比,STEMI组患者心电图上QTd、Tp-e及QTc均明显延长[（33.66±16.76）msvs.（55.29±31.12）ms,（89.55±12.61）msvs.（142.65±39.33）ms和（426.57±65.03）msvs.（482.26±48.03）ms,P〈0.001],且Tp-e/QT比值显著增加（0.21±0.03vs.0.29±0.07,P〈0.001）。120例STEMI患者中,发生恶性室性心律失常的有34例（28.3%）,心电图上QTd、Tp-e及QTc均较无恶性室性心律失常者延长,但只有Tp-e/QT比值显著增加（0.32±0.07vs.0.26±0.05,P〈0.000）。结论急性STEMI患者Tp-e/QT比值较健康成人明显延长,Tp-e/QT比值与恶性室性心律失常的发生有显著的相关性,可能是心脏性猝死最重要的预警指标之一。
Publisher
西安交通大学医学院第一附属医院心内科,陕西西安,710061%Main Line Health Heart Center and Lankenau Institute for Medical Research,Wynnewood,Pennsylvania,19096
Subject
