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微创经椎间孔腰椎间融合术联合经皮螺钉内固定融合术治疗退行性腰椎滑脱
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微创经椎间孔腰椎间融合术联合经皮螺钉内固定融合术治疗退行性腰椎滑脱
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微创经椎间孔腰椎间融合术联合经皮螺钉内固定融合术治疗退行性腰椎滑脱
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Journal Article
微创经椎间孔腰椎间融合术联合经皮螺钉内固定融合术治疗退行性腰椎滑脱
2016
Overview
目的探讨微创经椎间孔腰椎间融合术（MIS-TLIF）联合经皮螺钉内固定融合术治疗退行性腰椎滑脱的临床疗效。方法采用MIS-TLIF联合经皮螺钉内固定融合术共治疗32例退行性腰椎滑脱患者,比较术前和术后1周、3个月、末次随访时视觉模拟评分（VAS）、Oswestry功能障碍指数（ODI）和36条简明健康状况调查表（SF-36）评分,以及X线测量腰椎前凸角、冠状位Cobb角、冠状位和矢状位躯干偏移、腰椎滑脱程度（Meyerding分度）并计算滑脱率,X线或CT判断椎体融合率,MRI评价减压程度。结果 32例患者平均手术时间160 min,术中出血量120 ml,住院时间7.22 d,术后随访10.83个月。手术融合41个椎体节段,范围覆盖L2~S1节段。与术前相比,术后1周、3个月和末次随访时VAS（均P=0.000）和ODI（均P=0.000）评分增加,SF-36评分减少（P=0.002,0.000,0.000）,腰椎前凸角（均P=0.000）、冠状位Cobb角（均P=0.000）和滑脱率（均P=0.000）均减小。至末次随访时,ODI改善率为（80.51±6.02）%,椎体融合率达92.22%且螺钉位置均良好。32例患者中1例术后感染、2例脑脊液漏,经对症治疗均痊愈;无一例发生神经功能缺损等严重并发症、内固定失败、椎弓根螺钉和钛棒断裂或Cage移位,无一例死亡。结论 MIS-TLIF联合经皮螺钉内固定融合术创伤小、术中出血量少、并发症轻微、复位效果好、疗效确切,尽管存在手术时间较长、学习曲线较长、术中X线照射量较大等缺点,但仍是治疗退行性腰椎滑脱的有效方法。
Publisher
首都医科大学宣武医院神经外科,北京,100053
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