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天然反义转录物在神经系统疾病发病机制中的作用
by
相蕾\宋毅军
in
RNA
/ 神经系统疾病
/ 综述
2015
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天然反义转录物在神经系统疾病发病机制中的作用
by
相蕾\宋毅军
in
RNA
/ 神经系统疾病
/ 综述
2015
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Journal Article
天然反义转录物在神经系统疾病发病机制中的作用
2015
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Overview
天然反义转录物(NATs)在生物体内普遍存在。人们逐渐认识到NATs具有重要作用,能够调控基因表达。NATs在哺乳动物神经系统尤为普遍,其对神经系统正常生理功能有重要调节作用。NATs不仅参与神经元分化、髓鞘形成和离子通道调控,还参与突触可塑性和学习记忆等高级认知功能。本文重点讨论NATs在神经系统疾病尤其是神经变性病发病机制中的作用。
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