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Journal Article
抗N-甲基-D-天冬氨酸受体脑炎：三例报告并文献复习
2014
Overview
目的 回顾分析抗N-甲基-D-天冬氨酸受体（NMDAR）脑炎患者临床表现,总结其发病特点.方法与结果 共3例经临床、实验室和影像学检查明确诊断为抗NMDAR脑炎患者,男性2例、女性1例,年龄33 ～ 34岁,平均33.30岁.临床主要表现为头痛（2例）,精神异常（3例）,言语障碍（3例）,运动异常（1例）或幻觉（1例）;MRI显示脑回肿胀、颞叶异常信号或脱髓鞘改变;脑电图呈局灶性或弥漫性慢波;脑脊液白细胞计数（3例）和蛋白定量（2例）升高.均经甲泼尼龙和免疫球蛋白治疗痊愈.结论 抗NMDAR脑炎是一种严重但可治性疾病,是临床上可以鉴别且可用血清学方法诊断的疾病.早期诊断和及时治疗有助于改善抗NMDAR脑炎患者预后.
Publisher
300060,天津市环湖医院神经内科
Subject
