Journal Article

Short-term and long-term outcomes of single-incision plus one-port laparoscopic surgery for colorectal cancer: a propensity-matched cohort study with conventional laparoscopic surgery

Wu, Mingyi, Wang, Yanan, Mou, Tingyu, Shi, Jiaolong, Lan, Xiaoliang, Zhang, Xuehua, Wang, Hao

2023

Overview

Background Single-incision plus one-port laparoscopic surgery (SILS + 1) has been demonstrated to be minimally invasive while possessing better cosmesis and less pain compared with conventional laparoscopic surgery (CLS). However, SILS + 1 as an alternative to CLS for colorectal cancer is still controversial. Methods A total of 1071 patients who underwent curative laparoscopic surgery for colon cancer between 2015 and 2018 were included. Of these patients, 258 SILS + 1 cases and 516 CLS cases were analyzed using propensity score matching. The baseline characteristics, surgical outcomes, pathologic findings and recovery course, morbidity and mortality within postoperative 30 days and 3-year disease-free and overall survival were compared. Results Baseline characteristics were balanced between the groups. The mean operating time was significantly shorter in SILS + 1 group, with less estimated blood loss. Tumor size, tumor differentiation, number of harvested lymph nodes, resection margin and pathologic T, N, TNM stage was similar between the groups. There was no significant difference in overall perioperative complications. Uni- and multivariate analyses revealed that SILS + 1 was not a risk factor for complications. Postoperatively, SILS + 1 group showed faster recovery than CLS group in terms of ambulation, bowel function, oral intake and discharge. The 3-year disease-free survival rates of SILS + 1 and CLS groups were 90.1% and 87.3%(p = 0.59), respectively and the 3-year overall survival rates were 93.3% vs. 89.8%(p = 0.172). Discussion Our study revealed that SILS + 1 is safe, feasible, oncologically efficient, and may be considered as a surgical option for selected patients with colorectal cancer.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Abdomen / Antigens / Body mass index / Cancer / Care and treatment / Chemotherapy / Colon cancer / Colorectal cancer / Comparative analysis / Complications and side effects / Conventional laparoscopic surgery / Gastroenterology / Health aspects / Hepatology / Internal Medicine / Laparoscopic surgery / Laparoscopy / Learning curves / Lymph nodes / Lymphatic system / Medicine / Medicine & Public Health / Minimally invasive surgery / Morbidity / Mortality / Oncology, Experimental / Ostomy / Patient outcomes / Propensity-score match / Rectum / Risk factors / Single-incision plus one-port laparoscopic surgery / Surgeons / Surgery / Surgical outcomes / Survival / Tomography / Tumors