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陕西省出生缺陷的相关危险因素分析
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Journal Article
陕西省出生缺陷的相关危险因素分析
2011
Overview
目的探讨陕西省出生缺陷发生的影响因素,为采取有针对性的干预措施提供依据。方法应用分层随机整群抽样方法,抽取陕西省9市12个区县共124个乡镇。对终止妊娠日期发生在2007年10月至2009年7月间且孕满28周的13 273名妇女进行入户调查。要求妇女均为调查点的常住人口。收集完成围孕期状况调查的完整问卷有7 531份。采用SPSS 13.0软件对所有调查因素进行非条件Logistic回归分析。结果多因素Logistic回归模型中,按其贡献大小,危险因素由高到低依次为：父系家族出生缺陷史（OR=14.283）、孕期精神状态差（OR=10.835）、有不良孕产史（OR=8.264）、母亲居住农村（OR=5.067）、母亲孕期饮酒史（OR=4.598）、母亲年龄〉35岁（OR=3.696）、母亲孕期农药接触史（OR=3.507）、母亲孕期饮浓茶（OR=1.993）。孕期服用叶酸（OR=0.549）和家庭人均收入高（OR=0.422）为出生缺陷的保护因素。结论加强优生宣教,提高育龄妇女自我保健意识,改善居住环境,改变不良生活方式,对于降低出生缺陷发生风险尤为重要。
Publisher
西安交通大学医学院公共卫生系,陕西西安,710061
Subject
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