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自发性多部位脑出血临床研究
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自发性多部位脑出血临床研究
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自发性多部位脑出血临床研究
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Journal Article
自发性多部位脑出血临床研究
2016
Overview
目的总结自发性多部位脑出血（MICH）的临床特征。方法分别采取保守治疗、穿刺引流血肿清除术、血肿清除术和（或）去骨瓣减压术治疗30例自发性多部位脑出血和600例单一部位脑出血（SICH）患者;采用改良Rankin量表评价发病后3个月预后。结果与SICH组相比,MICH组患者高血压〉5年（P=0.008）、糖尿病（P=0.024）、高胆固醇血症（P=0.050）和缺血性卒中（P=0.026）发生率均较高,发病后平均动脉压升高（P=0.002）且多伴有肢体活动障碍（P=0.000）,基底节和丘脑为出血好发部位（P=0.001）。随访至发病后3个月,MICH组患者预后不良（P=0.006）。结论高血压〉5年、糖尿病、高胆固醇血症和缺血性卒中是诱发多部位脑出血的病理生理学基础,患者临床症状严重、远期生活质量差。
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