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Rotavirus Infection in Infants as Protection against Subsequent Infections
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Journal Article
Rotavirus Infection in Infants as Protection against Subsequent Infections
1996
Overview
Infections with group A rotaviruses are common among infants and young children worldwide.
1
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6
The outcome ranges from asymptomatic infection to severe, life-threatening diarrhea.
6
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10
Rotavirus is the leading cause of severe diarrhea among children and causes an estimated 870,000 deaths annually in developing countries.
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3
,
11
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12
The disease burden of rotavirus is so great that development of a vaccine is a global priority for public health.
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Epidemiologic studies of rotavirus have suggested that natural immunity is acquired after early exposure to the virus and that many children acquire immunity only after several infections.
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18
However, observations . . .
Publisher
Massachusetts Medical Society
Subject
/ Babies
/ Biological and medical sciences
/ Confounding Factors (Epidemiology)
/ Diarrhea, Infantile - classification
/ Diarrhea, Infantile - immunology
/ Diarrhea, Infantile - microbiology
/ Humans
/ Infant
/ Risk
/ Rotavirus - isolation & purification
/ Rotavirus Infections - immunology
/ Rotavirus Infections - microbiology
/ Vaccines
/ Viral diseases of the digestive system
/ Viruses
