Asset Details
Do you wish to reserve the book?
Microbial evolution through horizontal gene transfer by mobile genetic elements
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Microbial evolution through horizontal gene transfer by mobile genetic elements
Do you wish to request the book?
Microbial evolution through horizontal gene transfer by mobile genetic elements
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Microbial evolution through horizontal gene transfer by mobile genetic elements
2024
Overview
Mobile genetic elements (MGEs) are crucial for horizontal gene transfer (HGT) in bacteria and facilitate their rapid evolution and adaptation. MGEs include plasmids, integrative and conjugative elements, transposons, insertion sequences and bacteriophages. Notably, the spread of antimicrobial resistance genes (ARGs), which poses a serious threat to public health, is primarily attributable to HGT through MGEs. This mini‐review aims to provide an overview of the mechanisms by which MGEs mediate HGT in microbes. Specifically, the behaviour of conjugative plasmids in different environments and conditions was discussed, and recent methodologies for tracing the dynamics of MGEs were summarised. A comprehensive understanding of the mechanisms underlying HGT and the role of MGEs in bacterial evolution and adaptation is important to develop strategies to combat the spread of ARGs. This mini‐review explores the behaviour of conjugative plasmids in various environments, discusses recent methodologies for tracking mobile genetic elements (MGE) dynamics, and underscores the importance of understanding horizontal gene transfer (HGT) mechanisms to develop effective strategies against antimicrobial resistance genes (ARGs) dissemination.
