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Effect of high-flow nasal therapy on dyspnea, comfort, and respiratory rate
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Journal Article
Effect of high-flow nasal therapy on dyspnea, comfort, and respiratory rate
2019
Overview
Table 1 Summary of findings in studies of the HFNT with regard to dyspnea, comfort, and respiratory rate Study Type Design Intervention (N) Control (N) Treatment methods Measurement method Dyspnea Comfort Respiratory rate Bell N. [6] Emerg Med Australas 2015 AHRF RCT HFNT (48) COT (52) HFNT: flow 50 L/m, FiO2 30% titrated to SpO2 95% COT: discretion of the treating physician Dyspnea: Borg Scale Comfort: Likert Scale HFNT§ HFNT§ (1 h) HFNT§ (2 h) Frat J.P. [7] N Engl J Med 2015 AHRF RCT HFNT (106) COT (94) NIV (110) HFNT: flow 50 L/m, FiO2 100% then titrated to SpO2 92% COT: O2 titrated to SpO2 94% Dyspnea: VAS Comfort: VAS HFNT§ (10, 15, 30 min) NS HFNT§ (5, 10, 15, 30 min) AHFR acute hypoxemic respiratory failure, ARF acute respiratory failure, CPAP continuous positive airway pressure, COT conventional oxygen therapy, HFNT high-flow nasal treatment, h hours, IPAP inspiratory positive airway pressure, N number of patients, NA not available, NIV noninvasive ventilation, NS not statistically significant, PES esophageal pressure, PSV pressure support ventilation, RCT randomized controlled trial, VAS visual analog scale §Comparison between intervention and control with a statistically significant p value in favor of (the specified intervention) Heterogeneity in case-mix, the tools used for outcome assessment and measurement time-points precluded performance of meta-analysis. N Engl J Med. 2015;372:2185–96.View ArticleGoogle Scholar Lemiale V, Mokart D, Mayaux J, Lambert J, Rabbat A, Demoule A, Azoulay E. The effects of a 2-h trial of high-flow oxygen by nasal cannula versus Venturi mask in immunocompromised patients with hypoxemic acute respiratory failure: a multicenter randomized trial. Ann Emerg Med. 2017;70:465–472 e462.View ArticleGoogle Scholar Azoulay E, Lemiale V, Mokart D, Nseir S, Argaud L, Pene F, Kontar L, Bruneel F, Klouche K, Barbier F, Reignier J, Berrahil-Meksen L, Louis G, Constantin JM, Mayaux J, Wallet F, Kouatchet A, Peigne V, Theodose I, Perez P, Girault C, Jaber S, Oziel J, Nyunga M, Terzi N, Bouadma L, Lebert C, Lautrette A, Bige N, Raphalen JH, Papazian L, Darmon M, Chevret S, Demoule A. Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure: The HIGH Randomized Clinical Trial.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
