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Cognitive dysfunction in autoimmune rheumatic diseases

by Szekanecz, Zoltán , Oláh, Csaba , Denton, Christopher , Schwartz, Noa , Kardos, Zsófia , Putterman, Chaim

in Adalimumab / Anxiety / Arthritis / Atherosclerosis / Autoimmune diseases / Autoimmune Diseases - complications / Autoimmune Diseases - psychology / Blood-brain barrier / Chronic illnesses / Cognitive ability / Cognitive disorders / Cognitive dysfunction / Cognitive Dysfunction - etiology / Cognitive function / Cognitive therapy / Cytokines / Depression (Mood disorder) / Humans / Immunoglobulins / Inflammation / Lupus / Medicine / Medicine & Public Health / Memory / Neuropsychiatric lupus / Neurotoxicity / Orthopedics / Pathogenesis / Patient compliance / Quality of life / Review / Rheumatic diseases / Rheumatic Diseases - complications / Rheumatic Diseases - psychology / Rheumatoid arthritis / Rheumatoid factor / Rheumatology / Scleroderma / Scleroderma (Disease) / Social aspects / Systemic lupus erythematosus / Systemic sclerosis

2020

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Cognitive dysfunction in autoimmune rheumatic diseases

by Szekanecz, Zoltán , Oláh, Csaba , Denton, Christopher , Schwartz, Noa , Kardos, Zsófia , Putterman, Chaim

2020

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Cognitive dysfunction in autoimmune rheumatic diseases

by Szekanecz, Zoltán , Oláh, Csaba , Denton, Christopher , Schwartz, Noa , Kardos, Zsófia , Putterman, Chaim

2020

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Journal Article

Cognitive dysfunction in autoimmune rheumatic diseases

Szekanecz, Zoltán,

Oláh, Csaba,

Denton, Christopher,

Schwartz, Noa,

Kardos, Zsófia,

Putterman, Chaim

2020

Overview

For people with chronic autoimmune rheumatic diseases (AIRD), such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) or systemic sclerosis (SSc), normal cognitive functions are essential for performing daily activities. These diseases may be associated with cognitive dysfunction (CD). In RA, CD has been associated with age, lower education and disease duration and activity. Great advances have been achieved in neuropsychiatric SLE in the identification of pathogenic pathways, assessment and possible treatment strategies. SSc rarely exerts direct effects on the brain and cognitive function. However, the psychological burden that includes depression, anxiety and social impact may be high. AIRD patients with sustained disease activity, organ damage or lower education should be evaluated for CD. The control of systemic inflammation together with tailored behavioural cognitive therapies may benefit these patients.

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Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

Adalimumab

/ Anxiety

/ Arthritis

/ Atherosclerosis

/ Autoimmune diseases

/ Autoimmune Diseases - complications

/ Autoimmune Diseases - psychology