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COVID-19-associated optic neuritis - A case series and review of literature

by Kaliaperumal, Subashini , Sarkar, Sandip , Jossy, Ajax , Deb, Amit K , Jacob, Ninan , Gokhale, Tanmay

in Analysis / Autoantibodies / Care and treatment / Coronaviruses / COVID-19 / Demyelination / Diagnosis / Expedited Publications, Case Reports / Humans / Immune response / Intravenous administration / Methylprednisolone / Myelin / Myelin proteins / Myelin-Oligodendrocyte Glycoprotein / Neuritis / neuroophthalmic manifestation / Oligodendrocyte-myelin glycoprotein / Optic neuritis / Optic Neuritis - diagnosis / Optic Neuritis - drug therapy / Patients / Risk factors / SARS-CoV-2 / Steroid hormones

2022

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COVID-19-associated optic neuritis - A case series and review of literature

by Kaliaperumal, Subashini , Sarkar, Sandip , Jossy, Ajax , Deb, Amit K , Jacob, Ninan , Gokhale, Tanmay

2022

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COVID-19-associated optic neuritis - A case series and review of literature

by Kaliaperumal, Subashini , Sarkar, Sandip , Jossy, Ajax , Deb, Amit K , Jacob, Ninan , Gokhale, Tanmay

2022

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Journal Article

COVID-19-associated optic neuritis - A case series and review of literature

Kaliaperumal, Subashini,

Sarkar, Sandip,

Jossy, Ajax,

Deb, Amit K,

Jacob, Ninan,

Gokhale, Tanmay

2022

Overview

Neuroophthalmic manifestations are very rare in corona virus disease-19 (COVID-19) infection. Only few reports have been published till date describing COVID-19-associated neuroophthalmic manifestations. We, hereby, present a series of three cases who developed optic neuritis during the recovery period from COVID-19 infection. Among the three patients, demyelinating lesions were identified in two cases, while another case was associated with serum antibodies against myelin oligodendrocyte glycoprotein. All three patients received intravenous methylprednisolone followed by oral steroids according to the Optic Neuritis Treatment Trail ptotocol. Vision recovery was noted in all three patients, which was maintained at 2 months of the last follow up visit.

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Publisher

Medknow Publications & Media Pvt Ltd,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Wolters Kluwer - Medknow,Wolters Kluwer Medknow Publications

Subject

/ Expedited Publications, Case Reports

/ Humans

/ Immune response

/ Intravenous administration