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Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies
by
Ng, Chau Yee
, Hui, Rosaline Chung-Yee
, Yang, Chih-Hsun
, Chang, Ya-Ching
, Wu, Jennifer
, Wu, Ming-Ying
, Lu, Chun-Wei
, Chen, Chun-Bing
in
Animals
/ Antineoplastic Agents - adverse effects
/ Antineoplastic Agents - therapeutic use
/ Antineoplastic drugs
/ Antitumor agents
/ Cancer
/ Cancer therapies
/ Chemotherapy
/ Dermatology
/ Diagnosis, Differential
/ Drug therapy
/ Drug-Related Side Effects and Adverse Reactions - diagnosis
/ English literature
/ Exanthema
/ Humans
/ Hypersensitivity
/ Immunology
/ Immunosuppressive agents
/ Immunotherapy
/ Immunotherapy - adverse effects
/ Immunotherapy - methods
/ Medical research
/ Melanoma
/ Molecular Targeted Therapy - adverse effects
/ Morbidity
/ Mortality
/ Neoplasms - immunology
/ Neoplasms - therapy
/ Pharmacology
/ Review
/ Risk
/ Skin
/ Skin - pathology
/ Stevens-Johnson syndrome
/ Toxicity
2018
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Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies
by
Ng, Chau Yee
, Hui, Rosaline Chung-Yee
, Yang, Chih-Hsun
, Chang, Ya-Ching
, Wu, Jennifer
, Wu, Ming-Ying
, Lu, Chun-Wei
, Chen, Chun-Bing
in
Animals
/ Antineoplastic Agents - adverse effects
/ Antineoplastic Agents - therapeutic use
/ Antineoplastic drugs
/ Antitumor agents
/ Cancer
/ Cancer therapies
/ Chemotherapy
/ Dermatology
/ Diagnosis, Differential
/ Drug therapy
/ Drug-Related Side Effects and Adverse Reactions - diagnosis
/ English literature
/ Exanthema
/ Humans
/ Hypersensitivity
/ Immunology
/ Immunosuppressive agents
/ Immunotherapy
/ Immunotherapy - adverse effects
/ Immunotherapy - methods
/ Medical research
/ Melanoma
/ Molecular Targeted Therapy - adverse effects
/ Morbidity
/ Mortality
/ Neoplasms - immunology
/ Neoplasms - therapy
/ Pharmacology
/ Review
/ Risk
/ Skin
/ Skin - pathology
/ Stevens-Johnson syndrome
/ Toxicity
2018
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Do you wish to request the book?
Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies
by
Ng, Chau Yee
, Hui, Rosaline Chung-Yee
, Yang, Chih-Hsun
, Chang, Ya-Ching
, Wu, Jennifer
, Wu, Ming-Ying
, Lu, Chun-Wei
, Chen, Chun-Bing
in
Animals
/ Antineoplastic Agents - adverse effects
/ Antineoplastic Agents - therapeutic use
/ Antineoplastic drugs
/ Antitumor agents
/ Cancer
/ Cancer therapies
/ Chemotherapy
/ Dermatology
/ Diagnosis, Differential
/ Drug therapy
/ Drug-Related Side Effects and Adverse Reactions - diagnosis
/ English literature
/ Exanthema
/ Humans
/ Hypersensitivity
/ Immunology
/ Immunosuppressive agents
/ Immunotherapy
/ Immunotherapy - adverse effects
/ Immunotherapy - methods
/ Medical research
/ Melanoma
/ Molecular Targeted Therapy - adverse effects
/ Morbidity
/ Mortality
/ Neoplasms - immunology
/ Neoplasms - therapy
/ Pharmacology
/ Review
/ Risk
/ Skin
/ Skin - pathology
/ Stevens-Johnson syndrome
/ Toxicity
2018
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Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies
Journal Article
Anticancer Drugs Induced Severe Adverse Cutaneous Drug Reactions: An Updated Review on the Risks Associated with Anticancer Targeted Therapy or Immunotherapies
2018
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Overview
Cutaneous adverse drug reactions are commonly seen in patients with anticancer drug treatment. Anticancer drugs, including chemotherapy, target therapy, and recent immunotherapy causing skin reactions ranging from mild skin rash to life-threatening severe cutaneous adverse reactions (SCARs), such as Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) with increase morbidity and mortality while they are receiving cancer treatments, have been proposed to be a result of direct skin toxicity or drug hypersensitivity reactions (these are proposed mechanism, not definite). Differentiating SCARs from other more commonly seen reactions with a better outcome help prevent discontinuation of therapy and inappropriate use of systemic immunosuppressants for presumable allergic reactions, of which will affect the clinical outcome. In this article, we have reviewed published articles from 1950 to August 2017 for SJS/TEN associated with anticancer drugs, including chemotherapy, targeted therapy, and immunotherapy. We aimed to provide an overview of SJS/TEN associated with anticancer drugs to increase clinician recognition and accelerate future studies on the pathomechanism and managements.
Publisher
Hindawi Publishing Corporation,Hindawi,John Wiley & Sons, Inc,Wiley
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