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Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury
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Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury
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Journal Article
Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury
2016
Overview
Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury,substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic.
Publisher
Wolters Kluwer - Medknow Publications,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Department of Neurology, Henry Ford Hospital, Detroit, MI, USA,Medknow Publications & Media Pvt Ltd,Wolters Kluwer Medknow Publications
