Asset Details
Do you wish to reserve the book?
Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
Do you wish to request the book?
Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Improvement of Accuracy of Chromosome Aberration Analysis for Biological Radiation Dosimetry
2000
Overview
The frequency of chromosome aberrations in circulating lymphocytes is accepted as being the most reliable indicator of the absorbed dose of radiation. Researches done to improve the accuracy of cytogenetic analysis are described in this review. These include investigations of in vitro factors that affect the yield of radiation-induced aberrations and of in vivo factors that affect the chromosomal radiosensitivity of individuals. Improved chromosome-painting methods for accurate judgment of dicentrics and translocations are introduced. The practicality of these advanced cytogenetic techniques is shown by examinations of individuals exposed in the radiation accident at Tokaimura in 1999. INTRODUCTION Biological dosimetry based on chromosomal damage to peripheral blood lymphocytes after accidental overexposure to radiation was first performed in 1962 on victims of the Recuplex criticality accident in Hanford1). It is now accepted as being the most reliable means of estimating the radiation dose2). In view of the growing importance of cytogenetic analysis, in 1986 the IAEA established a practical standard methodology3). This has served as a valuable laboratory manual and made clear that chromosome analysis is time-consuming work that requires expert skills.
Publisher
THE JAPAN RADIATION RESEARCH SOCIETY,The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology,Oxford University Press
