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CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
by
Zhu, Qian
, Orkin, Stuart H.
, Liu, Nan
, Yuan, Guo-Cheng
in
Animal Genetics and Genomics
/ binding proteins
/ Binding sites
/ Bioinformatics
/ Biomedical and Life Sciences
/ Cancer
/ Chromatin
/ Chromatin - metabolism
/ Deoxyribonucleic acid
/ DNA
/ Endonuclease
/ Endonucleases
/ Evolutionary Biology
/ Footprinting
/ GATA1 Transcription Factor - analysis
/ Gene mapping
/ genome
/ Genomes
/ genomics
/ Human Genetics
/ Humans
/ Life Sciences
/ Microbial Genetics and Genomics
/ pipelines
/ Plant Genetics and Genomics
/ protein binding
/ Protein Footprinting - methods
/ Proteins
/ Sequence Alignment
/ Sequence Analysis, DNA
/ Software
/ Stem Cells - metabolism
/ Visualization
2019
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CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
by
Zhu, Qian
, Orkin, Stuart H.
, Liu, Nan
, Yuan, Guo-Cheng
in
Animal Genetics and Genomics
/ binding proteins
/ Binding sites
/ Bioinformatics
/ Biomedical and Life Sciences
/ Cancer
/ Chromatin
/ Chromatin - metabolism
/ Deoxyribonucleic acid
/ DNA
/ Endonuclease
/ Endonucleases
/ Evolutionary Biology
/ Footprinting
/ GATA1 Transcription Factor - analysis
/ Gene mapping
/ genome
/ Genomes
/ genomics
/ Human Genetics
/ Humans
/ Life Sciences
/ Microbial Genetics and Genomics
/ pipelines
/ Plant Genetics and Genomics
/ protein binding
/ Protein Footprinting - methods
/ Proteins
/ Sequence Alignment
/ Sequence Analysis, DNA
/ Software
/ Stem Cells - metabolism
/ Visualization
2019
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CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
by
Zhu, Qian
, Orkin, Stuart H.
, Liu, Nan
, Yuan, Guo-Cheng
in
Animal Genetics and Genomics
/ binding proteins
/ Binding sites
/ Bioinformatics
/ Biomedical and Life Sciences
/ Cancer
/ Chromatin
/ Chromatin - metabolism
/ Deoxyribonucleic acid
/ DNA
/ Endonuclease
/ Endonucleases
/ Evolutionary Biology
/ Footprinting
/ GATA1 Transcription Factor - analysis
/ Gene mapping
/ genome
/ Genomes
/ genomics
/ Human Genetics
/ Humans
/ Life Sciences
/ Microbial Genetics and Genomics
/ pipelines
/ Plant Genetics and Genomics
/ protein binding
/ Protein Footprinting - methods
/ Proteins
/ Sequence Alignment
/ Sequence Analysis, DNA
/ Software
/ Stem Cells - metabolism
/ Visualization
2019
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CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
Journal Article
CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis
2019
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Overview
We introduce CUT&RUNTools as a flexible, general pipeline for facilitating the identification of chromatin-associated protein binding and genomic footprinting analysis from antibody-targeted CUT&RUN primary cleavage data. CUT&RUNTools extracts endonuclease cut site information from sequences of short-read fragments and produces single-locus binding estimates, aggregate motif footprints, and informative visualizations to support the high-resolution mapping capability of CUT&RUN. CUT&RUNTools is available at
https://bitbucket.org/qzhudfci/cutruntools/
.
Publisher
BioMed Central,Springer Nature B.V
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