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Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks
by
De Las Rivas, Javier
, Fontanillo, Celia
in
Biochemistry/Bioinformatics
/ Biochemistry/Macromolecular Assemblies and Machines
/ Biology
/ Biophysics/Biomacromolecule-Ligand Interactions
/ Biophysics/Protein Chemistry and Proteomics
/ Computational Biology - methods
/ Computational Biology/Macromolecular Structure Analysis
/ Computational Biology/Systems Biology
/ Databases, Protein
/ Education
/ Experiments
/ Gene Regulatory Networks
/ Genomes
/ Humans
/ Molecular Biology/Bioinformatics
/ Protein Interaction Domains and Motifs
/ Protein-protein interactions
/ Proteins
/ Signal Transduction
2010
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Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks
by
De Las Rivas, Javier
, Fontanillo, Celia
in
Biochemistry/Bioinformatics
/ Biochemistry/Macromolecular Assemblies and Machines
/ Biology
/ Biophysics/Biomacromolecule-Ligand Interactions
/ Biophysics/Protein Chemistry and Proteomics
/ Computational Biology - methods
/ Computational Biology/Macromolecular Structure Analysis
/ Computational Biology/Systems Biology
/ Databases, Protein
/ Education
/ Experiments
/ Gene Regulatory Networks
/ Genomes
/ Humans
/ Molecular Biology/Bioinformatics
/ Protein Interaction Domains and Motifs
/ Protein-protein interactions
/ Proteins
/ Signal Transduction
2010
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Do you wish to request the book?
Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks
by
De Las Rivas, Javier
, Fontanillo, Celia
in
Biochemistry/Bioinformatics
/ Biochemistry/Macromolecular Assemblies and Machines
/ Biology
/ Biophysics/Biomacromolecule-Ligand Interactions
/ Biophysics/Protein Chemistry and Proteomics
/ Computational Biology - methods
/ Computational Biology/Macromolecular Structure Analysis
/ Computational Biology/Systems Biology
/ Databases, Protein
/ Education
/ Experiments
/ Gene Regulatory Networks
/ Genomes
/ Humans
/ Molecular Biology/Bioinformatics
/ Protein Interaction Domains and Motifs
/ Protein-protein interactions
/ Proteins
/ Signal Transduction
2010
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Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks
Journal Article
Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks
2010
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Overview
In many experimental assays, such generic interactions are rightfully filtered out. [...]the definition of PPI has to consider (1st) the interaction interface should be intentional and not accidental, i.e., the result of specific selected biomolecular events/forces; and (2nd) the interaction interface should be non-generic, i.e., evolved for a specific purpose distinct from totally generic functions such as protein production, degradation, and others. [...]the use of PPI data combined with related pathways allows for a useful and detailed exploration of protein networks.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Biochemistry/Macromolecular Assemblies and Machines
/ Biology
/ Biophysics/Biomacromolecule-Ligand Interactions
/ Biophysics/Protein Chemistry and Proteomics
/ Computational Biology - methods
/ Computational Biology/Macromolecular Structure Analysis
/ Computational Biology/Systems Biology
/ Genomes
/ Humans
/ Molecular Biology/Bioinformatics
/ Protein Interaction Domains and Motifs
/ Protein-protein interactions
/ Proteins
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