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Quality of Life after Radical Prostatectomy or Watchful Waiting
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Quality of Life after Radical Prostatectomy or Watchful Waiting
Quality of Life after Radical Prostatectomy or Watchful Waiting
Journal Article

Quality of Life after Radical Prostatectomy or Watchful Waiting

2002
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Overview
In this companion to the report by Holmberg et al. on survival in a randomized comparison of radical prostatectomy with watchful waiting among men with localized prostate cancer, sexual dysfunction and urinary leakage were more common in the radical-prostatectomy group, but the subjective quality of life in the two groups was similar. In a comparison of prostatectomy with watchful waiting, the quality of life in the two groups was similar. A man with newly diagnosed localized prostate cancer faces a frustrating choice of therapy. 1 He can defer treatment until symptoms appear (watchful waiting), undergo major surgery (radical prostatectomy), or receive radiotherapy (interstitial or external) with the intention of eliminating the tumor. 2 , 3 He may also receive hormonal therapy with antiandrogens or undergo castration. His choice may influence survival as well as the risk of therapy-induced acute or chronic symptoms. 4 Between 1989 and 1999, a group of Swedish urologists enrolled men with localized high-grade or moderate-grade prostate cancer in a randomized trial to compare radical prostatectomy with watchful waiting. 5 We examined . . .