Journal Article

A multi-tissue gene expression dataset for hibernating brown bears

Perry, Blair W., Quackenbush, Corey R., Evans Hutzenbiler, Brandon D., Kelley, Joanna L., Cornejo, Omar E., Jansen, Heiko T., Saxton, Michael W., Robbins, Charles T.

2023

Overview

Objectives Complex physiological adaptations often involve the coordination of molecular responses across multiple tissues. Establishing transcriptomic resources for non-traditional model organisms with phenotypes of interest can provide a foundation for understanding the genomic basis of these phenotypes, and the degree to which these resemble, or contrast, those of traditional model organisms. Here, we present a one-of-a-kind gene expression dataset generated from multiple tissues of two hibernating brown bears ( Ursus arctos ). Data description This dataset is comprised of 26 samples collected from 13 tissues of two hibernating brown bears. These samples were collected opportunistically and are typically not possible to attain, resulting in a highly unique and valuable gene expression dataset. In combination with previously published datasets, this new transcriptomic resource will facilitate detailed investigation of hibernation physiology in bears, and the potential to translate aspects of this biology to treat human disease.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Analysis / Animal Genetics and Genomics / Behavior / Biomedical and Life Sciences / Biosynthesis / Brown bear / Brown bears / data collection / Data entry / Data Note / Datasets / Dexmedetomidine / Diabetes / Gene expression / Genes / Genetic aspects / Genetics and Population Dynamics / Genomics / Heart / Hibernation / human diseases / Insulin resistance / Life Sciences / Liver / Metabolism / Methods / Microbial Genetics and Genomics / Phenotypes / Physiological aspects / Physiology / Plant Genetics and Genomics / RNA sequencing / Rodents / Transcriptomics / Ursus arctos / Zoological research