Journal Article

Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment

Jabbour, Pascal M., Starke, Robert M., Chalouhi, Nohra, Mouchtouris, Nikolaos, Rosenwasser, Robert H., Chitale, Ameet, Tjoumakaris, Stavropoula I.

2015

Overview

Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics.

• Publisher: Hindawi Publishing Corporation,John Wiley & Sons, Inc,Hindawi Limited,Wiley
• Subject: Brain diseases / Care and treatment / Diagnosis / Hemangioma, Cavernous, Central Nervous System - diagnosis / Hemangioma, Cavernous, Central Nervous System - surgery / Hemangioma, Cavernous, Central Nervous System - therapy / Hemorrhage / Humans / Lesions / Magnetic Resonance Imaging / Microsurgery / Neuroimaging / Patients / Physiological aspects / Radiosurgery / Review / Surgery