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Surface Modification of Intraocular Lenses
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Journal Article
Surface Modification of Intraocular Lenses
2016
Overview
Objective： This paper aimed to review the current literature on the surface modification ofintraocular lenses （IOLs）. Data Sources： All articles about surface modification of IOLs published up to 2015 were identified through a literature search on both PubMed and ScienceDirect. Study Selection： The articles on the surface modification of 1OLs were included, but those on design modification and surface coating were excluded. Results： Technology of surface modification included plasma, ion beam, layer-by-layer self-assembly, ultraviolet radiation, and ozone. The main molecules introduced into IOLs surface were poly （ethylene glycol）, polyhedral oligomeric silsesquioxane, 2-methacryloyloxyethyl phosphorylcholine, TiO2, heparin, F-heparin, titanium, titanium nitride, vinyl pyrrolidone, and inhibitors of cytokines. The surface modification either resulted in a more hydrophobic lens, a more hydrophilic lens, or a lens with a hydrophilic anterior and hydrophobic posterior surface. Advances in research regarding surface modification of ｜OLs had led to a better biocompatibility in both in vitro and animal experiments. Conclusion： The surface modification is an efficient, convenient, economic and promising method to improve the biocompatibility of IOLs.
Publisher
Wolters Kluwer - Medknow Publications,Medknow Publications and Media Pvt. Ltd,Lippincott Williams & Wilkins Ovid Technologies,Department of Ophthalmology, Navy General Hospital of PLA, Beijing 100048, China,Department of Ophthalmilogy, Third Clinical Medical College of Southern Medical University, Guangzhou, Guangdong 510515, China%Department of Ophthalmology, Hong Kong Laser Eye Center, Hong Kong 999077, China%Department of Ophthalmology,Medknow Publications & Media Pvt Ltd,Wolters Kluwer
Subject
/ Animals
/ Humans
/ Hydrophobic and Hydrophilic Interactions
/ Phosphorylcholine - analogs & derivatives
/ Phosphorylcholine - chemistry
/ Review
/ Studies
/ 乙烯基吡咯烷酮
/ 人工晶体
/ 文献检索
/ 生物相容性
/ 甲基丙烯酰
/ 紫外线辐射
/ 聚倍半硅氧烷
/ 表面改性
