Asset Details
Do you wish to reserve the book?
Bridging the Blood-Brain Barrier: New Methods Improve the Odds of Getting Drugs to the Brain Cells That Need Them
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Bridging the Blood-Brain Barrier: New Methods Improve the Odds of Getting Drugs to the Brain Cells That Need Them
Do you wish to request the book?
Bridging the Blood-Brain Barrier: New Methods Improve the Odds of Getting Drugs to the Brain Cells That Need Them
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Bridging the Blood-Brain Barrier: New Methods Improve the Odds of Getting Drugs to the Brain Cells That Need Them
2007
Overview
Brain diseases by the dozens lack effective therapies, but it's not for lack of trying, says Pardridge, a professor of medicine at the University of California, Los Angeles (United States): Pharmaceutical companies have failed to deliver effective new brain drugs, despite huge potential markets for Alzheimer disease, stroke, Parkinson disease, brain infections, and more. Strategy Debates Faking the brain out, however, is easier said than done, and according to Pardridge and other academic researchers, pharmaceutical companies have mostly botched the job.\\n Still others, including many drug companies, argue that no targeting is really needed, because the blood-brain barrier opens naturally during many diseases. The model, which is being produced by a spinoff company to sell to drug companies and researchers, can reproduce the properties of the healthy human blood-brain barrier as well as the altered blood-brain barrier of patients with multidrug-resistant epilepsy, according to a paper published online in February, 2007, in Epilepsia.
Publisher
Public Library of Science,Public Library of Science (PLoS)
