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Multiple Hyperpigmented Macules on Labial Mucosa with Longitudinal Melanonychia
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Multiple Hyperpigmented Macules on Labial Mucosa with Longitudinal Melanonychia
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Journal Article
Multiple Hyperpigmented Macules on Labial Mucosa with Longitudinal Melanonychia
2019
Overview
A 58-year-old female with a medical history of type 2 diabetes mellitus and arterial hypertension, presented with 3 months history of multiple hyperpigmented macules in the labial mucosa, hard palate, and tongue without any associated symptoms [Figure 1]a and [Figure 1]b. The patient was a nonsmoker and denied the use of any new medication that could cause the pigmentation. Diagnosis Due to the clinical findings of multiple hyperpigmented macules in oral and labial mucosa associated with longitudinal melanonychia in the absence of systemic disease, the patient was diagnosed with LHS. Differential diagnoses of this entity include Peutz-Jeghers syndrome (PJS), Addison's disease, Albright syndrome, Bandler syndrome, Cronkhite-Canada syndrome, melanoma, drug induced pigmentation (phenytoin, zidovudine, antimalarials, clofazimine and phenothiazine), hiperpigmentation due to smoking or heavy metal exposure and oral lichen planus.
Publisher
Wolters Kluwer - Medknow,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Wolters Kluwer Medknow Publications
