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The evolution of mendelian randomization for investigating drug effects
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Journal Article
The evolution of mendelian randomization for investigating drug effects
2022
Overview
Dipender Gill and Stephen Burgess discuss the accompanying study by James Yarmolinsky and colleagues investigating the associations between genetically-proxied inhibition of antihypertensive drug targets and risk of common cancer subtypes using Mendelian randomization.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Angiotensin-Converting Enzyme Inhibitors - adverse effects
/ Antihypertensive Agents - adverse effects
/ Blood Pressure - drug effects
/ Colorectal Neoplasms - chemically induced
/ Colorectal Neoplasms - epidemiology
/ Colorectal Neoplasms - genetics
/ Enzymes
/ Genetic Variation - drug effects
/ Genetic Variation - genetics
/ Genome-Wide Association Study - methods
/ Genome-Wide Association Study - trends
/ Humans
/ Identification and classification
/ Medicine
/ Medicine and Health Sciences
/ Mendelian Randomization Analysis - methods
/ Mendelian Randomization Analysis - trends
/ Methods
/ Non-pharmacological intervention
/ Proteins
