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Modernizing Reference Genome Assemblies

by Cunningham, Fiona , Trani, Lee , Mardis, Elaine R. , Matthews, Lucy , Pelan, Sarah , Chen, Hsiu-Chuan , Schneider, Valerie A. , Ritchie, Graham R.S. , Torrance, James , E. Eichler, Evan , Agarwala, Richa , Kremitzki, Colin , Wollam, Aye , Graves, Tina , Fulton, Lucinda , Threadgold, Glen , McLaren, William M. , Wood, Jonathan , Fulton, Robert , Harden, Glenn , Grafham, Darren , Church, Deanna M. , Rock, Susan , Wilson, Richard K. , Bouk, Nathan , Weinstock, George , Whitehead, Siobhan , Collins, Joanna , Howe, Kerstin , Auger, Katherine , Albracht, Derek , Kotkiewicz, Holland , Griffiths, Guy , Flicek, Paul , Dunn, Matthew , Hubbard, Tim , Kremitzki, Milinn , Chow, Will , Heath, Paul

in Biology / Biomedical research / Databases, Genetic / Genome, Human / Genomes / Genomics / Haplotypes / Humans / International Cooperation / Nucleotide sequencing / Physiological aspects

2011

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Modernizing Reference Genome Assemblies

in Biology / Biomedical research / Databases, Genetic / Genome, Human / Genomes / Genomics / Haplotypes / Humans / International Cooperation / Nucleotide sequencing / Physiological aspects

2011

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Modernizing Reference Genome Assemblies

in Biology / Biomedical research / Databases, Genetic / Genome, Human / Genomes / Genomics / Haplotypes / Humans / International Cooperation / Nucleotide sequencing / Physiological aspects

2011

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Journal Article

Modernizing Reference Genome Assemblies

Cunningham, Fiona,

Trani, Lee,

Mardis, Elaine R.,

Matthews, Lucy,

Pelan, Sarah,

Chen, Hsiu-Chuan,

Schneider, Valerie A.,

Ritchie, Graham R.S.,

Torrance, James,

E. Eichler, Evan,

Agarwala, Richa,

Kremitzki, Colin,

Wollam, Aye,

Graves, Tina,

Fulton, Lucinda,

Threadgold, Glen,

McLaren, William M.,

Wood, Jonathan,

Fulton, Robert,

Harden, Glenn,

Grafham, Darren,

Church, Deanna M.,

Rock, Susan,

Wilson, Richard K.,

Bouk, Nathan,

Weinstock, George,

Whitehead, Siobhan,

Collins, Joanna,

Howe, Kerstin,

Auger, Katherine,

Albracht, Derek,

Kotkiewicz, Holland,

Griffiths, Guy,

Flicek, Paul,

Dunn, Matthew,

Hubbard, Tim,

Kremitzki, Milinn,

Chow, Will,

Heath, Paul

2011

Overview

[...]we have developed a system to track individual regions that are under review. The primary assembly unit contains sequences for the non-redundant haploid assembly; this includes the scaffolds that make up the chromosome sequence as well as unplaced and unlocalized scaffolds that are thought to represent novel sequence (not shown in this picture).\\n Additionally, we wish to engage the research and clinical communities to identify regions that require targeted effort and to incorporate information from groups performing detailed work on specific loci.

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Publisher

Public Library of Science,Public Library of Science (PLoS)

Subject

Biology

/ Biomedical research

/ Genomes