Journal Article

Severe thrombotic complications secondary to antiphospholipid syndrome and undiagnosed systemic lupus erythematosus

Barber, Megan R.W., Clarke, Ann E., Adams, Corey D., Skeith, Leslie

2022

Overview

Barber et al discuss the case study of a 22-year-old man with intense pain in, dusky discoloration of and reduced sensation to his right foot. He had a history of migraines and 2 years of mild intermittent calf discomfort with exercise, for which he had not sought medical attention. He had a family history of premature coronary artery disease. Peripheral artery duplex ultrasonography showed reduced blood flow in both tibial arteries and a deep vein thrombosis in his right leg. Given the abnormal arterial flow, computed tomography (CT) angiography was ordered, which showed a chronic occlusion in the patient's right superficial femoral artery and an occluded infrarenal abdominal aorta with collateralization. Splenomegaly and axillary adenopathy were noted. He was treated with apixaban and referred to the vascular surgery team.

• Publisher: Elsevier Inc,CMA Impact Inc,CMA Impact, Inc
• Subject: Antibodies / Anticoagulants / Antiphospholipid syndrome / Antiphospholipid Syndrome - complications / Antiphospholipid Syndrome - diagnosis / Autoimmune diseases / Blood clot / Cardiovascular disease / Case studies / Complications and side effects / Coronary vessels / Hormone replacement therapy / Humans / Internal Medicine / Laboratories / Lupus / Lupus Erythematosus, Systemic - complications / Lupus Erythematosus, Systemic - diagnosis / Medical imaging / Obstetrics / Patients / Practice / Pregnancy / Risk factors / Systemic lupus erythematosus / Thrombosis / Thrombosis - complications / Vascular surgery / Vein & artery diseases